Results 21 to 30 of about 22,385 (313)
Als etabliertes Verfahren in verschiedenen sozial- und erziehungswissenschaftlichen Forschungsrichtungen lässt sich die qualitative Inhaltsanalyse an der Schnittstelle zwischen quantitativen und qualitativen Forschungszugängen verorten.
Sebastian Ruin
doaj +1 more source
The increasing use of digital media and technologies in sports pedagogical settings comes along with fundamental changes in basic sports pedagogical categories such as body, movement, and experience (Ruin & Giese, 2023).
Sebastian Ruin
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Att skapa ett forskningsprogram om Tid och Minne
The essay describes the background and creation of the large research program ”Time, Memory, and Representation. Recent Transformations in Historical Consciousness” (www.histcon.se), comprising twentyfive researchers representing twelve different ...
Hans Ruin
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Review of Risto Nurmela: Sigmund Freud und sein Bekenntnis zum Judesein in ’Der Mann Moses und die monoteistische Religion’. Wien: Lit Verlag, 2023.
Hans Ruin
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In his dissertation on Hegel’s conception of the State (1920), Franz Rosenzweig highlighted the role of Christianity in Hegel’s conception of the emergence of the universal.
Hans Ruin
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In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source

