Results 31 to 40 of about 316,519 (288)
Gambler's Ruin Bandit Problem [PDF]
, 2016 In this paper, we propose a new multi-armed bandit problem called the Gambler's Ruin Bandit Problem (GRBP). In the GRBP, the learner proceeds in a sequence of rounds, where each round is a Markov Decision Process (MDP) with two actions (arms): a ...
Akbarzadeh, Nima, Tekin, Cem
core +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Stocktaking methods of facilities in a state of ruin
Budownictwo i Architektura, 2019 The stocktaking is the basic form of presenting and protecting the object of the historic ruin. It also allows to monitor the behavior state and the degradation progress of an object.
Katarzyna Drobek +2 more
doaj +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Convexity of ruin probability and optimal dividend strategies for a general Levy process [PDF]
, 2014 In this paper, we consider the optimal dividends problem for a company whose cash reserves follow a general Levy process with certain positive jumps and arbitrary negative jumps.
Shen, Ying +2 more
core +4 more sources
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
La ruine angkorienne et le fromager : une mise en cloche d’un paysage fantasmé synonyme d’inaction ?
Projets de Paysage, 2019 From the rice paddies to the major urban centres, images of landscapes in the tropics circulating today take on a variety of forms. Although most of these representations correspond to reality, some are more of the realm of fantasy or come from another ...
Sébastien Preuil
doaj +1 more source
Integrated natural sciences approaches to the protection of medieval ruins
Ochrona Dziedzictwa Kulturowego, 2020 The aim of this paper is to present the Report of innovative restoration techniques, technologies and materials used in conservation in the context of natural sciences and heritage science of the RUINS Project.
Jakub Novotný, Jiří Bláha
doaj +1 more source
Effect of Stop-Loss Reinsurance on Primary Insurer Solvency
Risks, 2022 Stop-loss reinsurance is a risk management tool that allows an insurance company to transfer part of their risk to a reinsurance company. Ruin probabilities allow us to measure the effect of stop-loss reinsurance on the solvency of the primary insurer ...
Corina Constantinescu +4 more
doaj +1 more source