Results 51 to 60 of about 11,882,853 (287)
Application of Gegenbauer Polynomials with Two Variables to Bi-univalency of Generalized Discrete Probability Distribution Via Zero-Truncated Poisson Distribution Series [PDF]
Sahand Communications in Mathematical AnalysisThe present study is unique in exploring bi-univalent functions, which has recently garnered attention from many researchers in Geometric Function Theory (GFT).
Tunji Ibrahim Awolere +2 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
“Those foreigners ruin everything here”: Interactional functions of ethnic labelling among pupils in the Netherlands [PDF]
Journal of Sociolinguistics, 2019 AbstractThis paper contributes to a deeper understanding of ethnic labelling practices by examining their interactional functions among secondary school pupils in Venlo, the Netherlands. Pupils with migration backgrounds often labelled themselves and others “Turk,” “Moroccan,” or “foreigner,” and labelled others “Dutch.” The paper highlights that ...
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A note on scale functions and the time value of ruin for Lévy insurance risk processes [PDF]
Insurance: Mathematics and Economics, 2009 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Biffis, Enrico, Kyprianou, Andreas E.
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Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Elementary Bounds on the Ruin Capital in a Diffusion Model of Risk
Risks, 2014 In a diffusion model of risk, we focus on the initial capital needed to make the probability of ruin within finite time equal to a prescribed value. It is defined as a solution of a nonlinear equation.
Vsevolod K. Malinovskii
doaj +1 more source
Optimal Surplus-Dependent Reinsurance under Regime-Switching in a Brownian Risk Model
Risks, 2021 In this paper, we consider a company that wishes to determine the optimal reinsurance strategy minimising the total expected discounted amount of capital injections needed to prevent the ruin. The company’s surplus process is assumed to follow a Brownian
Julia Eisenberg +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
A note on some joint distribution functions involving the time of ruin [PDF]
Insurance: Mathematics and Economics, 2016 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +3 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source