Results 71 to 80 of about 66,699 (304)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

ADC 2005: 16th Australasian Database Conference [PDF]

, 2005
Rule-based classification systems have been widely used in real world applications because of the easy interpretability of rules. Many traditional rule-based classifiers prefer small rule sets to large rule sets, but small classifiers are sensitive to ...
Li, Jiuyong, Hu, Hong
core  

Acquiring Classifiers for Bipolarized Reward by XCS in a Continuous Reward Environment

SICE Journal of Control, Measurement, and System Integration, 2019
In data mining, it is important to clarify how effective the acquired rules are and which elements are affected by rule evaluation. Extended learning classifier system (XCS) reveals factors that affect the classifier (rule) evaluation by generalizing the
Takato Tatsumi, Keiki Takadama
doaj   +1 more source

Query Enrichment for Image Collections by Reuse of Classification Rules

Digital Presentation and Preservation of Cultural and Scientific Heritage, 2013
User queries over image collections, based on semantic similarity, can be processed in several ways. In this paper, we propose to reuse the rules produced by rule-based classifiers in their recognition models as query pattern definitions for searching ...
Nicolas Spyratos, Peter Stanchev, Krasimira Ivanova, Iliya Mitov   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Random Prism: An Alternative to Random Forests. [PDF]

, 2011
Ensemble learning techniques generate multiple classifiers, so called base classifiers, whose combined classification results are used in order to increase the overall classification accuracy.
Frederic Stahl, Stahl, F., Stahl, Frederic, Bramer, Max, Bramer, M., Max Bramer   +5 more
core   +1 more source

Symbiotic Evolution of Rule Based Classifiers [PDF]

, 2008
Genetic Algorithm is a widely used approach in predictive data mining where data mining output can be represented by If-Then rules and discovering the best rules is done by a genetic algorithm. The main motivation for using genetic algorithms in discovery of highlevel prediction rules is that they perform a global search in the problem space and cope ...
Ramin Halavati, Saeed Bagheri
openaire   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

A new sequential covering strategy for inducing classification rules with ant colony algorithms [PDF]

, 2012
Ant colony optimization (ACO) algorithms have been successfully applied to discover a list of classification rules. In general, these algorithms follow a sequential covering strategy, where a single rule is discovered at each iteration of the algorithm ...
Otero, Fernando E. B., Otero, Fernando E.B., Johnson, Colin G., Freitas, Alex A.   +3 more
core   +1 more source

Empirical analysis of tree-based classification models for customer churn prediction

Scientific African
Customer churn is a vital and reoccurring problem facing most business industries, particularly the telecommunications industry. Considering the fierce competition among telecommunications firms and the high expenses of attracting and gaining new ...
Fatima E. Usman-Hamza, Abdullateef O. Balogun, Salahdeen K. Nasiru, Luiz Fernando Capretz, Hammed A. Mojeed, Shakirat A. Salihu, Abimbola G. Akintola, Modinat A. Mabayoje, Joseph B. Awotunde   +8 more
doaj   +1 more source