Results 81 to 90 of about 22,758,962 (282)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Classification Based on Pruning and Double Covered Rule Sets for the Internet of Things Applications
The Scientific World Journal, 2014 The Internet of things (IOT) is a hot issue in recent years. It accumulates large amounts of data by IOT users, which is a great challenge to mining useful knowledge from IOT. Classification is an effective strategy which can predict the need of users in
Shasha Li, Zhongmei Zhou, Weiping Wang
doaj +1 more source
Multi-Objective Evolutionary Rule-Based Classification with Categorical Data
Entropy, 2018 The ease of interpretation of a classification model is essential for the task of validating it. Sometimes it is required to clearly explain the classification process of a model’s predictions. Models which are inherently easier to interpret can be
Fernando Jiménez +4 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
A general framework for designing a fuzzy rule-based classifier
Knowledge and Information Systems, 2010 This paper presents a general framework for designing a fuzzy rule-based classifier. Structure and parameters of the classifier are evolved through a two-stage genetic search. To reduce the search space, the classifier structure is constrained by a tree created using the evolving SOM tree algorithm.
Antanas Verikas +3 more
openaire +5 more sources
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Fuzzy modelling using a simplified rule base [PDF]
, 2004 Transparency and complexity are two major concerns of fuzzy rule-based systems. To improve accuracy and precision of the outputs, we need to increase the partitioning of the input space.
M. Shamim Khan +5 more
core
PLoS ONE, 2015 Microarray and beadchip are two most efficient techniques for measuring gene expression and methylation data in bioinformatics. Biclustering deals with the simultaneous clustering of genes and samples.
Ujjwal Maulik +3 more
doaj +1 more source
Optimizing Safety Logic Device Selection with Machine Learning: A Classifier-Based Comparison [PDF]
International Journal of Industrial Engineering and ManagementIn Industry 4.0 manufacturing, selecting appropriate safety logic devices during machinery risk assessment is critical yet complex. This study applies supervised machine learning classification to predict safety logic device categories.
Karel Stibor +2 more
doaj +1 more source
Detection of epilepsy with Electroencephalogram using rule-based classifiers
Neurocomputing, 2017 Epilepsy is a common neurological disorder, characterized by recurrent seizures. Electroencephalogram (EEG), a useful measure for analysing the brain's electrical activity, has been widely used for the detection of epileptic seizures. Most existing classification techniques are primarily aimed at increasing detection accuracy, while the ...
Guanjin Wang +2 more
openaire +2 more sources