Results 101 to 110 of about 22,758,962 (282)
Expressive and modular rule-based classifier for data streams [PDF]
, 2019 The advances in computing software, hardware, connected devices and wireless communication infrastructure in recent years have led to the desire to work with streaming data sources. Yet the number of techniques, approaches and algorithms which can work with data from a streaming source is still very limited, compared with batched data.
openaire +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
The role of classifiers in feature selection: Number vs nature [PDF]
, 2008 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Wrapper feature selection approaches are widely used to select a small subset of relevant features from a dataset.
Chrysostomou, Kyriacos Andrews
core +3 more sources
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Building Combined Classifiers [PDF]
, 2008 This chapter covers different approaches that may be taken when building an ensemble method, through studying specific examples of each approach from research conducted by the authors.
Eastwood, Mark, Gabrys, Bogdan
core +1 more source
Fuzzy rule based classifier model for evidence based clinical decision support systems
Intelligent Systems with ApplicationsClinicians benefit from the use of artificial intelligence and machine learning techniques applied to health data within health records, which identify commonalities between them.
Navin K, Mukesh Krishnan M․ B
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Accuracy of association rule based classifiers.
, 2015 Accuracy of association rule based classifiers.
Li Yao (113027) +2 more
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source