Results 101 to 110 of about 362,031 (306)

Primary Human Tissue Models for Metabolic Dysfunction‐Associated Liver Disease ‐ toward Streamlining Drug Discovery with Patient‐Derived Assays

Advanced Biology, EarlyView.
The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna, Nayere Taebnia, Yingxin Liang, Ningtao Cheng, Yi Wang, Maurice Michel, Volker M. Lauschke   +6 more
wiley   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

Advanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers, Maximilian Hausherr, Michel Lim, Karin Schork, Bilhan Karacora, Robin Grugel, Martin Eisenacher, Isabel Gil Aldea, Peter Riederer, Manfred Gerlach, Katrin Marcus   +10 more
wiley   +1 more source

Using unsupervised corpus-based methods to build rule-based machine translation systems [PDF]

, 2009
Tesis doctoral en Informática realizada en la Universitat d’Alacant por Felipe Sánchez Martínez bajo la dirección de los doctores Juan Antonio Pérez Ortiz y Mikel L. Forcada.
Sánchez-Martínez, Felipe
core   +1 more source

Engineering the Link: From Genome Interaction Maps to Functional Insight

Advanced Biology, EarlyView.
Advances in chromosome conformation capture have revealed the genome's 3D organization, yet its causal impact on gene regulation remains elusive. This review highlights emerging genome‐engineering tools ‐ zinc fingers, TALEs, and CRISPR‐Cas9 ‐ that enable targeted manipulation of chromatin loops to dissect structure–function relationships. It discusses
Frido Petersen, Simon Westermann, Valeriia Smialkovska, Jan Mathony, Angelika Feldmann, Dominik Niopek   +5 more
wiley   +1 more source

A Different Perspective on the Solid Lubrication Performance of Black Phosphorus: Friend or Foe?

Advanced Engineering Materials, EarlyView.
Researchers investigate black phosphorus (BP) as a standalone solid lubricant coating through ball‐on‐disc linear‐reciprocating sliding experiments in dry conditions. Testing on different metals shows BP doesn't universally reduce friction and wear. However, it achieves 33% friction reduction on rougher iron surfaces and 23% wear reduction on aluminum.
Matteo Vezzelli, Manel Rodríguez Ripoll, Sabine Schwarz, Ali Erdemir, Maria Clelia Righi, Carsten Gachot   +5 more
wiley   +1 more source

Machine Learning Applied to High Entropy Alloys under Irradiation

Advanced Engineering Materials, EarlyView.
Designing alloys for extreme environments demands fast, trustworthy prediction. This review charts how machine learning—especially machine‐learned interatomic potentials and predictive models based on experiment‐informed datasets—captures the complexity of high‐entropy alloys in extreme environments, predicts phase formation, mechanical properties, and
Amin Esfandiarpour, Sri Tapaswi Nori, Silvia Bonfanti, Mikko Alava, Antoni Wadowski, Wenyi Huo, Łukasz Kurpaska, Michał Pecelerowicz, Jan S. Wróbel   +8 more
wiley   +1 more source

Greek Idioms Processing in the Machine Translation System CAT2 [PDF]

, 2011
This paper describes Machine Translation (MT) and the associated processing of idioms. Particularly, this research examines the rule-based CAT 2 MT system and experiments with Greek sentences containing idioms.
Anastasiou, Dimitra
core  

Additive Processing of Ti‐17 by Wire Arc Directed Energy Deposition: An Investigation of the Microstructure and Mechanical Properties

Advanced Engineering Materials, EarlyView.
This study focuses on processing the titanium alloy Ti‐17 using wire arc directed energy deposition (waDED), with an emphasis on the microstructure and mechanical properties. The waDED typical heat‐affected zone banding is characterized and related to the local mechanical properties.
Alexander Wenda, Thomas Klein, Florian Fahrnberger, Marcel Czipin, Karin Hartl, Clemens Simson, Martin Stockinger, Herbert Hutter   +7 more
wiley   +1 more source

Research Progress of Named Entity Recognition Based on Large Language Model [PDF]

Jisuanji kexue yu tansuo
Named entity recognition aims to identify named entities and their types from unstructured text, which is an important basic task in natural language processing technologies such as question answering system, machine translation and knowledge graph. With
LIANG Jia, ZHANG Liping, YAN Sheng, ZHAO Yubo, ZHANG Yawen
doaj   +1 more source

Development and Preliminary In Vivo Study of 3D‐Printed Bioactive Glass Scaffolds with Trabecular Architecture

Advanced Engineering Materials, EarlyView.
This study reports the fabrication of trabecular bioactive glass scaffolds (composition “1d”: 46.1SiO2‐28.7CaO‐8.8MgO‐6.2P2O5‐5.7CaF2‐4.5Na2O wt%) through vat photopolymerization and the relevant results from mechanical testing and in vivo implantation procedures in rabbit femora, showing great promise for bone tissue engineering applications.
Dilshat Tulyaganov, Roberta Gabrieli, Avzal Akbarov, Nigora Nigmatova, Bekhzod Khabilov, Alessandro Schiavi, Martin Schwentenwein, Enrica Verné, Francesco Baino   +8 more
wiley   +1 more source