Results 271 to 280 of about 328,604 (299)

SIRT3‐Mediated Deacetylation of DRP1K711 Prevents Mitochondrial Dysfunction in Parkinson's Disease

Advanced Science, EarlyView.
SIRT3‐mediated deacetylation of DRP1 at K711 resists mitochondrial dysfunction and DA neuronal death in PD, uncovering a treatment target. Abstract Dysregulation of mitochondrial dynamics is a key contributor to the pathogenesis of Parkinson's disease (PD).
Ye Xi, Kai Tao, Xiaomin Wen, Dayun Feng, Zifan Mai, Hui Ding, Honghui Mao, Mingming Wang, Qian Yang, Jie Xiang, Jie Zhang, Shengxi Wu   +11 more
wiley   +1 more source

Harnessing Artificial Intelligence in Obesity Research and Management: A Comprehensive Review. [PDF]

Diagnostics (Basel)
Azmi S, Kunnathodi F, Alotaibi HF, Alhazzani W, Mustafa M, Ahmad I, Anvarbatcha R, Lytras MD, Arafat AA.   +8 more
europepmc   +1 more source

Applications of Artificial Intelligence in Drug Repurposing

Advanced Science, EarlyView.
Artificial intelligence algorithms are transforming drug repurposing by revealing new therapeutic targets and mechanisms. This review highlights the integration of AI frameworks, multimodal datasets, and advanced optimization methods, accelerating the discovery of new indications for existing drugs.
Zhaoman Wan, Xinran Sun, Yi Li, Tianyao Chu, Xueyu Hao, Yang Cao, Peng Zhang   +6 more
wiley   +1 more source

Accurate, Robust, and Scalable Machine Abstraction of Mayo Endoscopic Subscores From Colonoscopy Reports. [PDF]

Inflamm Bowel Dis
Silverman AL, Bhasuran B, Mosenia A, Yasini F, Ramasamy G, Banerjee I, Gupta S, Mardirossian T, Narain R, Sewell J, Butte AJ, Rudrapatna VA.   +11 more
europepmc   +1 more source

Shared and Unique Neural Codes for Biological Motion Perception in Humans and Macaque Monkeys

Advanced Science, EarlyView.
Cross‐species fMRI studies reveal distinct neural mechanisms for biological motion (BM) processing. In humans, the posterior superior temporal sulcus (hpSTS) selectively responds to conspecific BM, while monkeys process BM from both species in the middle temporal area (MT).
Yuhui Cheng, Yumeng Xin, Xiqian Lu, Tianshu Yang, Xiaohan Ma, Xiangyong Yuan, Ning Liu, Yi Jiang   +7 more
wiley   +1 more source

Probabilistic and deep learning approaches for conductivity-driven nanocomposite classification. [PDF]

Sci Rep
Gazehi W, Loukil R, Besbes M.
europepmc   +1 more source

The DID-guide: A guide to developing digital mental health interventions. [PDF]

Internet Interv
Mertens ECA, Van Gelder JL.
europepmc   +1 more source

Text mining for disease surveillance in veterinary clinical data: part two, training computers to identify features in clinical text. [PDF]

Front Vet Sci
Davies H, Nenadic G, Alfattni G, Arguello Casteleiro M, Al Moubayed N, Farrell S, Radford AD, Noble PM.   +7 more
europepmc   +1 more source

MolNexTR: a generalized deep learning model for molecular image recognition. [PDF]

J Cheminform
Chen Y, Leung CT, Huang Y, Sun J, Chen H, Gao H.   +5 more
europepmc   +1 more source

Development and validation of a deep learning-based automated computed tomography image segmentation and diagnostic model for infectious hydronephrosis: a retrospective multicentre cohort study. [PDF]

EClinicalMedicine
Lai C, Hu Z, Zhu J, Dai M, Qi X, Zhai Q, Luo Y, Deng C, Shi J, Li Z, Wu Z, Liao X, Zhao Y, Bi X, Zhou Y, Liu C, Huang X, Xu K.   +17 more
europepmc   +1 more source