Results 51 to 60 of about 349,833 (278)
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
Hybrid rule-based - example-based MT: feeding apertium with sub-sentential translation units [PDF]
, 2009 This paper describes a hybrid machine translation (MT) approach that consists of integrating bilingual chunks (sub-sentential translation units) obtained from parallel corpora into an MT system built using the Apertium free/open-source rule-based machine
Forcada, Mikel +2 more
core +3 more sources
From rule-based models to deep learning transformers architectures for natural language processing and sign language translation systems: survey, taxonomy and performance evaluation [PDF]
Artificial Intelligence ReviewWith the growing Deaf and Hard of Hearing population worldwide and the persistent shortage of certified sign language interpreters, there is a pressing need for an efficient, signs-driven, integrated end-to-end translation system, from sign to gloss to ...
Nada Shahin, Leila Ismail
semanticscholar +1 more source
Molecular Oncology, EarlyView.Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit +19 more
wiley +1 more source
An open source rule induction tool for transfer-based SMT [PDF]
, 2009 In this paper we describe an open source tool for automatic induction of transfer rules. Transfer rule induction is carried out on pairs of dependency structures and their node alignment to produce all rules consistent with the node alignment.
Graham, Yvette, van Genabith, Josef
core +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Tokenisation in rule-based machine translation [PDF]
, 2023 Tokenisation is a process, where text is converted into such form, where each item is separated from the rest of the text. Words, for example, are such items, and they must be separated from punctuation marks and diacritics. The most convenient way to do
Hurskainen, Arvi
core
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source