Results 31 to 40 of about 21,209 (255)
A Framework for Simulating Cyclists in SUMO
SUMO Conference Proceedings, 2023 Cyclists pose an interesting challenge in the microscopic modeling and simulation of urban traffic. Like motorists, cyclists can move on roadways, tend to have one main axis of movement (longitudinal), and cannot change their velocity instantaneously ...
Heather Kaths, Aboozar Roosta
doaj +1 more source
RULE‐GOVERNED BEHAVIOR AND SENSITIVITY TO CHANGING CONSEQUENCES OF RESPONDING [PDF]
Journal of the Experimental Analysis of Behavior, 1986 Humans were presented with a task that required moving a light through a matrix. Button presses could produce light movements according to a multiple fixed‐ratio 18/differential‐reinforcement‐of‐low‐rate 6‐s schedule, with components alternating every 2 min. Moving the light through the maze earned points worth chances on money prizes.
S C, Hayes +4 more
openaire +2 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Efeitos de instruções sobre respostas de checagem
Psicologia: Teoria e PesquisaO estudo teve o objetivo de testar o controle verbal de diferentes instruções sobre respostas de checagem. Dois participantes adultos foram instruídos a separar quatro tipos de sementes misturadas.
Paulo Roberto Abreu +1 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Actions, action sequences and habits: evidence that goal-directed and habitual action control are hierarchically organized. [PDF]
PLoS Computational Biology, 2013 Behavioral evidence suggests that instrumental conditioning is governed by two forms of action control: a goal-directed and a habit learning process. Model-based reinforcement learning (RL) has been argued to underlie the goal-directed process; however ...
Amir Dezfouli, Bernard W Balleine
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source