Results 41 to 50 of about 594 (217)
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Osculating Type Ruled Surfaces of B-Lift Curves
MathematicsInthis paper, we introduce a family of ruled surfaces called the osculating type (OT) ruled surfaces of a B-Lift curve. By taking into account an alternative frame on the surface, we obtain more simplified geometric invariants of the surface.
Yanlin Li +4 more
doaj +1 more source
A computational study of ruled surfaces
Journal of Symbolic Computation, 2009 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Busé, Laurent +2 more
openaire +3 more sources
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
How phagocytic cells kill bacteria: Lessons from a professional killer
FEBS Open Bio, EarlyView.How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley +1 more source
Ruled Surfaces in Elliptic Space [PDF]
Proceedings of the American Mathematical Society, 1970 Bonnet's theorem on ruled surfaces [2, p. 449] deals solely with intrinsic properties if an intrinsic definition of the line of striction is adopted. Contrasting this, our aim is to define the parameter of distribution and the line of striction in relation to the enveloping space and to show that they have the usual properties. Attention will be called
openaire +2 more sources
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Holomorphic Foliations in Ruled Surfaces [PDF]
Transactions of the American Mathematical Society, 1989 We analyse the universal families of holomorphic foliations with singularities in a ruled surface. In terms of Chern classes we determine the general and the special families. We also classify all nonsingular foliations.
openaire +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source