Results 31 to 40 of about 26,738 (260)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
ON RULED SURFACES IN MINKOWSKl SPACES [PDF]
Communications of the Korean Mathematical Society, 2003 Summary: We study ruled surfaces in Minkowski space, which admit 1-type Gauss map. In particular, non-cylindric-al ruled surfaces with finite type Gauss map are of \(k\)-type (\(k\geq2\)).
Kim, Dong-Soo +2 more
openaire +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Characterizations of Spatial Quaternionic Partner-Ruled Surfaces
AxiomsIn this paper, we investigate the spatial quaternionic expressions of partner-ruled surfaces. Moreover, we formulate the striction curves and dralls of these surfaces by use of the quaternionic product.
Soley Ersoy +2 more
doaj +1 more source
On the Singularities of Surfaces Ruled by Conics [PDF]
Communications in Algebra, 2014 16 pages, 13 ...
BRUNDU, MICHELA, SACCHIERO, GIANNI
openaire +3 more sources
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Motion of Bishop Frenet Offsets of Ruled Surfaces in E3
Journal of Applied Mathematics, 2015 The main goal of this paper is to study the motion of two associated ruled surfaces in Euclidean 3-space E3. In particular, the motion of Bishop Frenet offsets of ruled surfaces is investigated.
H. N. Abd-Ellah
doaj +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source