Results 41 to 50 of about 28,712 (296)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Motion of Bishop Frenet Offsets of Ruled Surfaces in E3

open access: yesJournal of Applied Mathematics, 2015
The main goal of this paper is to study the motion of two associated ruled surfaces in Euclidean 3-space E3. In particular, the motion of Bishop Frenet offsets of ruled surfaces is investigated.
H. N. Abd-Ellah
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Generalized ruled surfaces in Myller configuration [PDF]

open access: yes
In this paper, we introduce a quite big ruled surface family, which is called generalized ruled surfaces with Frenet-type frame in Myller configuration for Euclidean 3-space.
Tosun, Murat   +2 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

STUDY ON THE PROJECTION WITH ELEVATIONS OF HELICOID-TYPE SURFACES

open access: yesJournal of Industrial Design and Engineering Graphics, 2017
This paper presents right helicoid surfaces in various systems of representation. Emphasis was put on the representation of helicoid surfaces in the projection with elevations, where both the right helicoid with a perpendicular axis on the elevated plan ...
CRISAN TUDOREANU Adrian, DRAGAN Delia
doaj  

Simulation of Spray Painting Using Articulated – Arm Robot [PDF]

open access: yesEngineering and Technology Journal, 2015
Robot trajectory generation for spray painting have highly demand in modern manufacturing. One of the most common surfaces in spray painting operations is ruled surfaces.
Alaa Hassan Shabeeb   +1 more
doaj   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Ruled surfaces (Ruled surfaces in Lorentz spaces)

open access: yes, 1997
In this thesis, correspondences to notions such as ruled surfaces, their striction points and curves, distribution parameter, developabi- Jity of surfaces and main theorems related to these which are well- known in the 3-dimensional Euclid space, are ...
Çelik, Yaşar
core   +1 more source

Cissoid constructions of augmented rational ruled surfaces [PDF]

open access: yes, 2018
Given two real affine rational surfaces we derive a criterion for deciding the rationality of their cissoid. Furthermore, when one of the surfaces is augmented ruled and the other is either an augmented ruled or an augmented Steiner surface, we prove ...
Peternell, Martin; orcid:   +2 more
core   +2 more sources

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