Results 51 to 60 of about 122,024 (261)

Administrative Freezing of Capital Construction

open access: yesСибирское юридическое обозрение, 2015
The author estimates administrative freezing of capital construction as a type of punishment for violating laws in this sphere. The article provides the mechanism of freezing of capital construction as a serious alternative for fine sanctions.
A. V. Kropacheva
doaj   +2 more sources

Study on the influence of standoff distance on substrate damage under an abrasive water jet process by molecular dynamics simulation

open access: yesFriction, 2017
The process of a cluster-containing water jet impinging on a monocrystalline silicon substrate was studied by molecular dynamics simulation. The results show that as the standoff distance increases, the jet will gradually diverge.
Ruling Chen, Di Zhang, Yihua Wu
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Misinterpreting Mislabelling: The Psagot Ruling

open access: yesEuropean Papers, 2020
(Series Information) European Papers - A Journal on Law and Integration, 2019 4(3), 763-777 | Insight | (Table of Contents) I. Introduction. - II. The CJEU recourse to international law in decisions on disputed territories. - III.
Olia Kanevskaia
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Digitocracy: Ruling and Being Ruled

open access: yesPhilosophies, 2020
Digitalisation is attracting much scholarly attention at present. However, scholars often take its benefits for granted, overlooking the essential question: “Does digital technology make us better?” This paper aims to help fill this gap by examining ...
Alfonso Ballesteros
doaj   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

From rules to rule patterns [PDF]

open access: yes, 1996
Rule-based systems are a commonly accepted solution for smoothly capturing the context-dependent and time-dependent organizational knowledge of large enterprises, also known as business policies. At the same time, however, the design of rule-based applications is one of the most pressing open research problems. This is largely because of the expressive
Gerti Kappel   +3 more
openaire   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Juridical-Fiqhi Investigation of the Legal and Ethical Rulings on Physician's Responsibility Regarding Abortion [PDF]

open access: yesپژوهش‌های فقهی مسائل مستحدثه
Abortion may be motivated by the concealment of the heinous act of adultery and the preservation of family honor, the necessity of saving the mother's life when the continuation of pregnancy threatens the life of the mother or the fetus, the prevention ...
Parviz Bagheri, abdulgabar zargoshnasab
doaj   +1 more source

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