Results 31 to 40 of about 42,063 (170)

Time to consider ruling out inclusion bodies denaturing protocols for spontaneous solubilization of biologically active proteins

Scientific Reports
The formation of inclusion bodies (IBs) in microbial cell factories is a very common process occurring during recombinant protein production. Different protocols have been developed for the extraction of soluble proteins from IBs using several strategies,
Ricardo Baltà-Foix, Elena Garcia-Fruitós, Anna Arís   +2 more
doaj   +1 more source

Inhibition of STING-mediated antiviral innate immunity activation by CD97 via modulation of ER-phagy

Communications Biology
Endoplasmic reticulum (ER) autophagy (ER-phagy) is a vital homeostatic process triggered by multiple signals and plays a crucial role in regulating innate immunity and viral replication.
Huasong Chang, Rukun Yang, Wenjing Qi, Peili Hou, Aibiao Xiang, Xiaoyu Liu, Ran Kang, Hongmei Wang, Hongbin He   +8 more
doaj   +1 more source

Dietary protein levels modulate the gut microbiome composition through fecal samples derived from lactating ewes

Frontiers in Endocrinology, 2023
In ruminants, the digestion and utilization of dietary proteins are closely linked to the bacterial populations that are present in the gastrointestinal tract.
Jiachong Liang, Sikandar Ali, Sikandar Ali, Chunrong Lv, Hongyuan Yang, Xiaoqi Zhao, Xiaojun Ni, Chunyan Li, Baiji Danzeng, Yajing Wang, Guobo Quan   +10 more
doaj   +1 more source

PAWR augments anti-RNA viral innate immunity by promoting the PIM2-XBP1s-RIG-I signaling axis

Nature Communications
PRKC Apoptosis WT1 Regulator (PAWR) has been implicated in tumorigenesis. However, its role in antiviral innate immunity remains unexplored. Here, we demonstrate that PAWR transcriptionally upregulates RIG-I expression through the transcription factor X ...
Peili Hou, Xiaonan Sun, Hongchao Zhu, Yueyue Feng, Rui Li, Xiaoyun Wang, Fuzhen Zhang, Jun Wang, Yuanyuan Han, Daniel Chang He, Hongmei Wang, Hongbin He   +11 more
doaj   +1 more source

Ultrastructural changes in endothelial cells of buffaloes following in-vitro exposure to Pasteurella multocida B:2

BMC Veterinary Research, 2020
Background Pasteurella multocida B:2 causes haemorrhagic septicaemia in cattle and buffaloes. However, buffaloes are found to be more susceptible to the infection than cattle.
Yulianna Puspitasari, Annas Salleh, Mohd Zamri-Saad   +2 more
doaj   +1 more source

Kimchi cabbage (Brassica rapa L.) by-products treated with calcium oxide and alkaline hydrogen peroxide as feed ingredient for Holstein steers

Journal of Animal Science and Technology, 2021
This study aimed to investigate the effects of Kimchi cabbage by-products either treated or untreated with calcium oxide (CaO) and alkaline hydrogen peroxide (AHP) as substitutional ingredient of total mixed ration
A-Rang Son, Seon-Ho Kim, Raniel A. Valencia, Chang-Dae Jeong, Mahfuzul Islam, Chul-Ju Yang, Sang-Suk Lee   +6 more
doaj   +1 more source

Mycotoxins in ruminants [PDF]

Proceedings of the Nutrition Society, 1969
Mycotoxins have for long been associated with disease and death in animals, but because of the great variety of fungi present in animal feedstuffs and the detailed investigations needed to establish a causal relationship between mycotoxin and a clinical disease, few disease ...
openaire   +2 more sources

Exploring the therapeutic potential of recombinant bovine β-defensins for antimicrobial and anti-inflammatory functions in sepsis management

Veterinary Research
β-defensins are multifunctional peptides of the host immune system involved in responses to infectious diseases. We investigated the potential of five recombinant proteins based on bovine β-defensins (bovine neutrophil β-defensins (BNBD) 1, 2, 3, and 4 ...
Cristina Saubi, Ricardo Baltà-Foix, Jose Vicente Carratalá, Francesc Fàbregas, Daniel Sandín, Marc Torrent, Elena Garcia-Fruitós, Anna Arís   +7 more
doaj   +1 more source

Multipathway synergy promotes testicular transition from growth to spermatogenesis in early-puberty goats

BMC Genomics, 2020
Background The microscopic process of postnatal testicular development in early-puberty animals is poorly understood. Therefore, in this study, 21 male Yiling goats with average ages of 0, 30, 60, 90, 120, 150 and 180 days old (each age group comprised ...
Dongdong Bo, Xunping Jiang, Guiqiong Liu, Feng Xu, Ruixue Hu, Teketay Wassie, Yuqing Chong, Sohail Ahmed, Chenhui Liu, Shishay Girmay   +9 more
doaj   +1 more source

Remplacement partiel des protéines du lait par celles du blé ou du maïs dans les aliments d’allaitement : influence sur l’utilisation digestive chez le veau de boucherie

INRAE Productions Animales, 1990
Le but de cet essai était d’étudier l’influence du remplacement d’une partie des protéines du lait par celles du blé ou du maïs, sur la digestibilité de l’aliment et la rétention azotée, chez le veau de boucherie.
R. TOULLEC, J.F. GRONGNET, H. FLAGEUL, J. LAREYNIE, P.M. LUCAS   +4 more
doaj   +1 more source