Results 31 to 40 of about 40,670 (269)

Toward Nano‐Nutritional Medicine: A Remotely Activated Trans‐Vaccenic Acid‐Based Lipid Nanoparticles for Enhancing Immune Checkpoint Blockade Therapy

Advanced Science, EarlyView.
Eutectic mixtures from trans‐vaccenic acid (TVA) and stearic acid, which served as phase‐change material to encapsulate IR780, forming NIR‐responsive nanoparticles. IR780@TVA LNPs induce photothermal therapy and initiate adaptive anti‐tumor immunity.
Kang Liu, Yunlong Li, Hanmeng Liu, Peng Zhang, Mingjing Wang, Quanwei Sun, Wenshuo Yang, Zhengwei Song, Song Tan, Ye Yang, Peng She, Dengke Yin, Wei Shen   +12 more
wiley   +1 more source

Immunomodulatory activities of bovine host defense peptides (HDPs): context-dependent roles in inflammation and immune priming

BMC Veterinary Research
Background Maintaining immune homeostasis is essential for livestock health and productivity, particularly in the face of infection or stress. Host defense peptides (HDPs), including β-defensins and cathelicidins, are key innate immune components with ...
Cristina Saubi, Kieran G. Meade, Sergi Travé-Asensio, Elena Garcia-Fruitós, Anna Aris   +4 more
doaj   +1 more source

Effect of Isolation Ruminal Yeast from Ruminants on In Vitro Ruminal Fermentation

Veterinary Sciences
In order to obtain high-performing yeast strains from ruminants, it is necessary to select them from species such as beef cattle, dairy cows, goats, and buffalo. A total of 91 isolated yeasts were collected using the standard methods of microbial culture on agar medium followed by streaking on a plate at least three times until pure yeast colonies were
Krung Wilachai, Pramote Paengkoum, Nittaya Taethaisong, Pirat Thitisak, Kriengsak Poonsuk, Juan J. Loor, Siwaporn Paengkoum   +6 more
openaire   +3 more sources

A Single‐Cell Transcriptomic Atlas of the Ovine Rumen Microbiome Characterizes Lineage‐Specific Metabolic Shifts Associated with Host Heat Tolerance

Advanced Science, EarlyView.
An optimized single‐cell transcriptomic framework profiles over 60 000 cells to map the ovine rumen microbiome, partitioning the ecosystem into seven cross‐species functional clusters. In heat‐resistant hosts, a lineage‐specific metabolic shift in Anaerovibrio lipolyticus toward a highly glycolytic phenotype contributes to a “nutritional sparing ...
Sanbao Zhang, Qinyang Jiang, Junjie Ma, Jianwei Zou, Fan Wang, Feifei Lv, Yanna Huang, Yongcheng Wang, Ziye Xu   +8 more
wiley   +1 more source

Time to consider ruling out inclusion bodies denaturing protocols for spontaneous solubilization of biologically active proteins

Scientific Reports
The formation of inclusion bodies (IBs) in microbial cell factories is a very common process occurring during recombinant protein production. Different protocols have been developed for the extraction of soluble proteins from IBs using several strategies,
Ricardo Baltà-Foix, Elena Garcia-Fruitós, Anna Arís   +2 more
doaj   +1 more source

Dietary protein levels modulate the gut microbiome composition through fecal samples derived from lactating ewes

Frontiers in Endocrinology, 2023
In ruminants, the digestion and utilization of dietary proteins are closely linked to the bacterial populations that are present in the gastrointestinal tract.
Jiachong Liang, Sikandar Ali, Sikandar Ali, Chunrong Lv, Hongyuan Yang, Xiaoqi Zhao, Xiaojun Ni, Chunyan Li, Baiji Danzeng, Yajing Wang, Guobo Quan   +10 more
doaj   +1 more source

A Global Methane Observation System to Reduce Uncertainty for Anthropogenic and Natural Sources and Sinks for Detecting and Attributing Climate Feedbacks

Advanced Science, EarlyView.
Conceptual illustration of a Global Ecosystem Methane Observing System (GEM‐OS) integrating satellites, aircraft, atmospheric networks, and ecosystem measurements to quantify methane emissions from anthropogenic and natural sources. The multi‐scale observing framework improves source attribution, reduces uncertainty in regional methane budgets, and ...
P. Ciais, S. Peng, J. Chang, F. Li, Q. Zhu, K. Yuan, G. Hugelius, H. Li, Y. Cai, F. Chevallier, K. Tibrewal, E. A. Kort, K. Arndt, J. Watts, B. Buma, N. Besic, P. I. Palmer, H. Cadillo‐Quiroz, E. Euskirchen, M. J. Gondwe, A. Hoyt, R. Jackson, S. Malone, D. Monteverde, S. Natali, M. Ramonet, C. Rey‐Sanchez, L. B. Sagang, E. A. G. Schuur, R. Vargas, R. Varner, Z. Zhang, B. Poulter   +32 more
wiley   +1 more source

Inhibition of STING-mediated antiviral innate immunity activation by CD97 via modulation of ER-phagy

Communications Biology
Endoplasmic reticulum (ER) autophagy (ER-phagy) is a vital homeostatic process triggered by multiple signals and plays a crucial role in regulating innate immunity and viral replication.
Huasong Chang, Rukun Yang, Wenjing Qi, Peili Hou, Aibiao Xiang, Xiaoyu Liu, Ran Kang, Hongmei Wang, Hongbin He   +8 more
doaj   +1 more source

Kimchi cabbage (Brassica rapa L.) by-products treated with calcium oxide and alkaline hydrogen peroxide as feed ingredient for Holstein steers

Journal of Animal Science and Technology, 2021
This study aimed to investigate the effects of Kimchi cabbage by-products either treated or untreated with calcium oxide (CaO) and alkaline hydrogen peroxide (AHP) as substitutional ingredient of total mixed ration
A-Rang Son, Seon-Ho Kim, Raniel A. Valencia, Chang-Dae Jeong, Mahfuzul Islam, Chul-Ju Yang, Sang-Suk Lee   +6 more
doaj   +1 more source

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source