Results 41 to 50 of about 78,465 (305)

Time to consider ruling out inclusion bodies denaturing protocols for spontaneous solubilization of biologically active proteins

Scientific Reports
The formation of inclusion bodies (IBs) in microbial cell factories is a very common process occurring during recombinant protein production. Different protocols have been developed for the extraction of soluble proteins from IBs using several strategies,
Ricardo Baltà-Foix, Elena Garcia-Fruitós, Anna Arís   +2 more
doaj   +1 more source

ELF5‐Mediated Enhancer–Promoter Interaction Regulates LALBA Expression in Ovine Mammary Gland

Advanced Science, EarlyView.
In the study, we systematically investigate the epigenetic mechanisms underlying lactation traits in sheep by integrating transcriptomic, chromatin accessibility, histone modification, and functional analyses. We identify a super‐enhancer at the LALBA locus and demonstrate that enhancer E4 functions as its core regulatory element.
Xinmiao Wu, Jiqing Wang, Zhiyun Hao, Mingna Li, Huimin Zhen, Yuan Liu, Guoyong Zhao, Chunyan Ren, Xuelan Zhou, Haixiong Hu, Mingjie Li, Nan Shi   +11 more
wiley   +1 more source

Inhibition of STING-mediated antiviral innate immunity activation by CD97 via modulation of ER-phagy

Communications Biology
Endoplasmic reticulum (ER) autophagy (ER-phagy) is a vital homeostatic process triggered by multiple signals and plays a crucial role in regulating innate immunity and viral replication.
Huasong Chang, Rukun Yang, Wenjing Qi, Peili Hou, Aibiao Xiang, Xiaoyu Liu, Ran Kang, Hongmei Wang, Hongbin He   +8 more
doaj   +1 more source

Kimchi cabbage (Brassica rapa L.) by-products treated with calcium oxide and alkaline hydrogen peroxide as feed ingredient for Holstein steers

Journal of Animal Science and Technology, 2021
This study aimed to investigate the effects of Kimchi cabbage by-products either treated or untreated with calcium oxide (CaO) and alkaline hydrogen peroxide (AHP) as substitutional ingredient of total mixed ration
A-Rang Son, Seon-Ho Kim, Raniel A. Valencia, Chang-Dae Jeong, Mahfuzul Islam, Chul-Ju Yang, Sang-Suk Lee   +6 more
doaj   +1 more source

The Power of Unity: Collective Action and Smallholder Agricultural Performance in West Africa

Agribusiness, EarlyView.
ABSTRACT We analyze the impact of collective action through farmer‐based organizations (FBOs) on smallholders' farm performance and income inequality in Ghana, Benin, The Gambia, and Mali. We find that FBO membership increases cereal yield in Ghana and The Gambia, legume yield in Mali, ruminant numbers in Benin and The Gambia, and total farm income in ...
Emmanuel Donkor, Bright Owusu Asante, David Boansi, Victor Owusu   +3 more
wiley   +1 more source

PAWR augments anti-RNA viral innate immunity by promoting the PIM2-XBP1s-RIG-I signaling axis

Nature Communications
PRKC Apoptosis WT1 Regulator (PAWR) has been implicated in tumorigenesis. However, its role in antiviral innate immunity remains unexplored. Here, we demonstrate that PAWR transcriptionally upregulates RIG-I expression through the transcription factor X ...
Peili Hou, Xiaonan Sun, Hongchao Zhu, Yueyue Feng, Rui Li, Xiaoyun Wang, Fuzhen Zhang, Jun Wang, Yuanyuan Han, Daniel Chang He, Hongmei Wang, Hongbin He   +11 more
doaj   +1 more source

Exploring the Impact of Meat Alternative Labeling Regulations on the U.S. Meat Consumption Patterns

Agribusiness, EarlyView.
ABSTRACT The global demand for conventional meat continues to rise, but it is also associated with substantial environmental and health challenges. In response, meat alternatives have gained popularity, sparking debates over meat alternative labeling regulations. This study investigates the effects of meat alternative labeling regulations in the United
Jeong Hun Ji, Sang Hyeon Lee
wiley   +1 more source

Exploring the therapeutic potential of recombinant bovine β-defensins for antimicrobial and anti-inflammatory functions in sepsis management

Veterinary Research
β-defensins are multifunctional peptides of the host immune system involved in responses to infectious diseases. We investigated the potential of five recombinant proteins based on bovine β-defensins (bovine neutrophil β-defensins (BNBD) 1, 2, 3, and 4 ...
Cristina Saubi, Ricardo Baltà-Foix, Jose Vicente Carratalá, Francesc Fàbregas, Daniel Sandín, Marc Torrent, Elena Garcia-Fruitós, Anna Arís   +7 more
doaj   +1 more source

Ultrastructural changes in endothelial cells of buffaloes following in-vitro exposure to Pasteurella multocida B:2

BMC Veterinary Research, 2020
Background Pasteurella multocida B:2 causes haemorrhagic septicaemia in cattle and buffaloes. However, buffaloes are found to be more susceptible to the infection than cattle.
Yulianna Puspitasari, Annas Salleh, Mohd Zamri-Saad   +2 more
doaj   +1 more source

Dietary protein levels modulate the gut microbiome composition through fecal samples derived from lactating ewes

Frontiers in Endocrinology, 2023
In ruminants, the digestion and utilization of dietary proteins are closely linked to the bacterial populations that are present in the gastrointestinal tract.
Jiachong Liang, Sikandar Ali, Sikandar Ali, Chunrong Lv, Hongyuan Yang, Xiaoqi Zhao, Xiaojun Ni, Chunyan Li, Baiji Danzeng, Yajing Wang, Guobo Quan   +10 more
doaj   +1 more source