Results 111 to 120 of about 33,338 (216)
Fatty acid composition and phospholipid types used in infant formulas modifies the establishment of human gut bacteria in germ-free mice [PDF]
Human milk fat contains high concentrations of medium-chained fatty acids (MCFA) and triacylglycerols emulsified by a sphingomyelin-rich phospholipid membrane (milk phospholipids, MPL).
Bennike, Rikke Mette Guldhammer +2 more
core +1 more source
We provide the first comprehensive analysis of changes in the gut bacteriome at different clinical stages of HTLV‐1 infection. HTLV‐1 infection is associated with a dysbiosis that includes reduced bacterial diversity and an inverted Firmicutes/Bacteroidetes ratio.
Lorena Abreu Fernandes +8 more
wiley +1 more source
APOE genotype influences the gut microbiome structure and function in humans and mice: relevance for Alzheimer’s disease pathophysiology [PDF]
Apolipoprotein E (APOE) genotype is the strongest prevalent genetic risk factor for Alzheimer’s disease (AD). Numerous studies have provided insights into the pathologic mechanisms.
Corsini, Simone +10 more
core +1 more source
This study analyzed gut microbiota in older adults with and without Frailty Syndrome by 16S rRNA gene sequencing and metagenomics. Frailty was associated with altered microbial composition, metabolic functions, and increased antimicrobial resistance, whereas non‐frail individuals showed healthier profiles.
Ana Barberá +5 more
wiley +1 more source
This study examines the mechanism by which alfalfa saponin (AS) regulates intestinal stemness via modulation of the gut microbiota. The results indicate that AS significantly increases the abundance of Lactobacillus intestinalis, which subsequently activates Wnt signaling via bile acid metabolism and enhances intestinal stemness. These findings provide
Mengqi Liu +8 more
wiley +1 more source
Abstract Alzheimer's disease (AD) is projected to become the highest‐burden neurological disorder globally. Mounting evidence implicates the gut microbiome in AD pathogenesis. This scoping review of gut microbiomes in mild cognitive impairment (MCI) and AD included dietary and probiotic interventions.
Alison Warren +10 more
wiley +1 more source
Overview of study design. Metagenomic and plasma/fecal metabolomic studies were performed in 44 NSCLC patients who underwent neoadjuvant tislelizumab therapy plus platinum ‐ based doublet chemotherapy. Abstract Background Neoadjuvant anti‐programmed cell death 1 (PD‐1) immunochemotherapy has shown promising efficiency in the treatment of early‐stage ...
Ailing Cao +11 more
wiley +1 more source
This study shows that almond polysaccharide AP1 relieves DSS‐induced UC in mice by restoring the mucosal barrier, suppressing inflammation, and modulating gut microbiota and SCFA metabolism. ABSTRACT The development of new therapeutic strategies for ulcerative colitis (UC) requires the targeting of multiple pathogenic factors, including disruption of ...
Yanqi Peng +7 more
wiley +1 more source
Polysaccharides from Irpex lacteus alleviated kidney inflammatory response. PCP could reverse the phenotype of MRL/lpr mice, reduce autoantibody levels, alleviate inflammatory responses, and improve renal function. Improving the body's metabolism by gut microbes may be the possible mechanism of PCP in treating LN.
Guoxin Ji +9 more
wiley +1 more source
Background Faecalibacterium prausnitzii is a ubiquitous member of the human gut microbiome, constituting up to 15% of the total bacteria in the human gut. Substantial evidence connects decreased levels of F.
Cormac Brian Fitzgerald +6 more
doaj +1 more source

