Results 81 to 90 of about 33,338 (216)

Underlying Mechanisms of the Treatment Efficacy of (R, S)‐Ketamine for Post‐Traumatic Stress Disorder and Depression: A Review

Medicine Advances, EarlyView.
Research shows that (R, S)‐ketamine and its stereoisomers effectively reduce symptoms of post‐traumatic stress disorder (PTSD) and treatment‐resistant depression, with (R)‐ketamine offering similar benefits with fewer side effects. Evidence highlights specific neural circuits and regions, including the dentate gyrus, prefrontal cortex, vCA3, dorsal ...
Thomas Edward Cutting, Richard Evans Hartman   +1 more
wiley   +1 more source

Comparison of the Intestinal Microbiome of Italian Patients with Multiple Sclerosis and Their Household Relatives

Life, 2021
Multiple sclerosis (MS) is a chronic immune-mediated disease of the central nervous system, caused by a combination of genetic and environmental factors. In recent years, a role in MS pathogenesis was assigned to the gut microbiota.
Paola Galluzzo, Fanny Claire Capri, Luca Vecchioni, Sabrina Realmuto, Luca Scalisi, Salvatore Cottone, Domenico Nuzzo, Rosa Alduina   +7 more
doaj   +1 more source

The Dietary Intervention of Transgenic Low-Gliadin Wheat Bread in Patients with Non-Celiac Gluten Sensitivity (NCGS) Showed No Differences with Gluten Free Diet (GFD) but Provides Better Gut Microbiota Profile [PDF]

, 2018
The study evaluated the symptoms, acceptance, and digestibility of bread made from transgenic low-gliadin wheat, in comparison with gluten free bread, in Non-coeliac gluten sensitivity (NCGS) patients, considering clinical/sensory parameters and gut ...
Comino Montilla, Isabel María, García Molina, María Dolores, Giménez, María J., Haro, Carmen, Ozuna Serafini, Carmen Victoria, Pastor, Jorge, Segura Montero, Verónica, Sousa Martín, Carolina, Sánchez León, Susana, Vaquero, Luis, Villatoro, Myriam   +10 more
core   +1 more source

Nanoformulated Diacerein Alleviates Hyperlipidemia via Gut Microbiota Modulation In Vivo

Nano Select, EarlyView.
A nanoformulation of diacerein (Nano‐DIA) was fabricated with carboxymethyl cellulose, achieving enhanced solubility and rapid dissolution for alternative anti‐hyperlipidemia therapeutics. Mechanistic studies revealed its in vivo lipid‐lowering efficacy is through metabolite‐mediated and microbiota‐dependent manner, highlighting its dual action on host
Zheng Peng, Yi Yu, Mingyi Chen, Weibin Wu, Chunyan Zhu, Caisheng Wu, Weihua Li, Zehua Liu, Qiang Xie   +8 more
wiley   +1 more source

Insights into Butyrate Production in a Controlled Fermentation System via Gene Predictions

mSystems, 2017
Butyrate is a common fatty acid produced in important fermentative systems, such as the human/animal gut and other H2 production systems. Despite its importance, there is little information on the partnerships between butyrate producers and other ...
S. Esquivel-Elizondo, Z. E. Ilhan, E. I. Garcia-Peña, R. Krajmalnik-Brown   +3 more
doaj   +1 more source

Lower systemic inflammation is associated with gut firmicutes dominance and reduced liver injury in a novel ambulatory model of parenteral nutrition

Annals of Medicine, 2022
Background Total Parenteral Nutrition (TPN) provides lifesaving nutritional support to patients unable to maintain regular enteral nutrition (EN). Unfortunately, cholestasis is a significant side effect affecting 20–40% of paediatric patients.
Ashish Samaddar, Johan van Nispen, Austin Armstrong, Eric Song, Marcus Voigt, Vidul Murali, Joseph Krebs, Chandra Manithody, Christine Denton, Aaron C. Ericsson, Ajay Kumar Jain   +10 more
doaj   +1 more source

The Nasal Microbiome and Associations With Environmental Exposures and Respiratory Health

Allergy, EarlyView.
This study evaluates the association of the nasal microbiome with air pollutants, meteorological conditions, and respiratory health in adolescents. Bacterial diversity is positively associated with hay fever and short‐term NO2 exposure, and negatively with temperature. A Moraxella‐dominated nasotype is linked to lower O3 exposure and higher temperature
Javier Perez‐Garcia, Anne K. Bozack, Sheryl L. Rifas‐Shiman, Yanjiao Zhou, Joanne Sordillo, Brent Coull, Heike Luttmann‐Gibson, Joel Schwartz, Marie‐France Hivert, Emily Oken, Diane R. Gold, Andres Cardenas   +11 more
wiley   +1 more source

Prebiotic, Probiotic, and Synbiotic Supplementation in Chronic Kidney Disease: A Systematic Review and Meta-analysis [PDF]

, 2019
Gut dysbiosis has been implicated in the pathogenesis of chronic kidney disease (CKD). Restoring gut microbiota with prebiotic, probiotic, and synbiotic supplementation has emerged as a potential therapeutic intervention but has not been systematically ...
Campbell, Katrina L., Johnson, David W., McFarlane, Catherine, Ramos, Christiane I.   +3 more
core   +1 more source

Pseudoruminococcus massiliensis gen. nov., sp. nov., a new bacterium isolated from the human gut microbiota

New Microbes and New Infections, 2020
Pseudoruminococcus massiliensis strain Marseille-P3876T (= CSUR P3876) is a new genus from the family Ruminococcaceae that was isolated from the gut microbiota of a healthy Senegalese man.
P. Afouda, G. Dubourg, T.T. Nguyen, D. Raoult, P.-E. Fournier   +4 more
doaj   +1 more source

Lactobacillus rhamnosus GG-supplemented formula expands butyrate-producing bacterial strains in food allergic infants. [PDF]

, 2015
Dietary intervention with extensively hydrolyzed casein formula supplemented with Lactobacillus rhamnosus GG (EHCF+LGG) accelerates tolerance acquisition in infants with cow's milk allergy (CMA).
A Huurre, Aly A Khan, AM Branum, AM Eren, Andrew T Stefka, Antonio Calignano, AT Stefka, B Bjorksten, C De Filippo, C Ferrario, Cathryn R Nagler, D Ghadimi, E Mileti, E Pohjavuori, EY Hsiao, GM Nava, H Sokol, H Sokol, I Cho, J Penders, J Wang, Jack A Gilbert, JG Caporaso, JG Caporaso, JN Paulson, K Atarashi, K Atarashi, KA Donato, Lorella Paparo, M Kalliomaki, M Kalliomaki, MJ Cox, N Arpaia, N Kalliomaki, Naseer Sangwan, NJ Osborne, P Louis, P Van den Abbeele, PJ McMurdie, PM Smith, R Berni Canani, R Berni Canani, R Berni Canani, R Berni Canani, RC Edgar, Rita Nocerino, Roberto Berni Canani, Rosita Aitoro, S Miquel, SH Duncan, SH Sicherer, SL Prescott, SR Lele, T Feehley, T Raveh-Sadka, The Human Microbiome Project Consortium, Y Furusawa, Y Nagano   +57 more
core   +2 more sources