Results 131 to 140 of about 11,022,643 (271)
Physics‐encoded transfer learning for scale‐up modeling of CHO cell bioreactors
Abstract Developing reliable predictive models for mammalian cell bioreactors, particularly Chinese hamster ovary (CHO) cultures widely used in biopharmaceutical manufacturing, remains challenging due to severe data scarcity in industrial‐scale reactors.
Muyang Li, Ming Xiao, Zhe Wu
wiley +1 more source
On the accuracy of Runge-Kutta’s method [PDF]
openaire +1 more source
This article provides important geometric formulas for node‐centered, edge‐based schemes in any number of dimensions. These formulas are noteworthy, as they do not require the explicit formation of dual regions. We prove several key geometric results, with a particular focus on the four‐dimensional case, due to potential space‐time applications ...
Nicholas Tufillaro +2 more
wiley +1 more source
Pharmacokinetic modelling is extensively used in understanding drug behavior, distribution and optimizing dosing regimens. This study presents a two-compartment pharmacokinetic model developed using three numerical approaches that includes the Euler ...
Kaniz Fatima +5 more
doaj +1 more source
Subspace Acceleration for Efficient Nonlinear Water Wave Simulation
We introduce an exponentially weighted subspace acceleration technique to reduce GMRES iterations for solving the Poisson equation with time‐dependent coefficients in nonlinear, dispersive free‐surface flows governed by the incompressible Navier‐Stokes equations. The method significantly reduces memory requirements and computational complexity compared
Rasmus Kleist Hørlyck Sørensen +3 more
wiley +1 more source
QG‐Python is an open, reproducible 1.5‐layer quasi‐geostrophic modelling service whose published diagnostics show that the classical von Neumann bound underestimates the true Leapfrog stability limit by a factor of 13.7, and that the Robert–Asselin–Williams filter reduces kinetic energy and enstrophy biases from ~21% and ~45% to under 4%.
Elias D. Nino‐Ruiz
wiley +1 more source
ABSTRACT This paper proposes a Machine Learning (ML)‐enabled estimator‐controller design framework, in which a parameterized Model Predictive Controller (MPC) and a parameterized Moving Horizon Estimator (MHE) are jointly refined using Bayesian Optimization (BO).
Hossein Nejatbakhsh Esfahani +1 more
wiley +1 more source
Abstract Machine learning offers a flexible route to constitutive modeling, with two emergent questions for geoscience applications: what level of thermodynamic constraint should be embedded in the network architecture, and how should predictive uncertainty be quantified when extrapolating from laboratory to field conditions? We address both challenges
Kangan Li +3 more
wiley +1 more source
A Stochastic Model for Fog Forecasting
Abstract Despite significant advancements in parameterizations of boundary layer processes, forecasting, and nowcasting low‐level clouds using numerical models remain challenging. The purpose of this study is to test a prototype of a high‐resolution stochastic‐deterministic model designed to simulate the life cycle of fog cover based on the Ising model
E. Cardoso‐Bihlo, B. Khouider
wiley +1 more source

