Results 41 to 50 of about 2,026 (216)

Reassessing Bone Marrow Aspirate and Trephine Biopsies in Staging for Paediatric and Young Adult Patients With Ewing Sarcoma and Rhabdomyosarcoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ewing sarcoma (ES) and rhabdomyosarcoma (RMS) are aggressive malignancies in children and adolescents where metastases impact prognosis. 18F‐fluoro‐2‐deoxy‐d‐glucose positron emission tomography/computed tomography (FDG‐PET/CT) and bone marrow aspirate and trephine biopsies (BMAT) are used to identify disease involvement.
Imogen Andrews   +3 more
wiley   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola   +4 more
wiley   +1 more source

An interdisciplinary, co-designed guide for return to running postpartum—a mixed-methods study

open access: yesFrontiers in Sports and Active Living
IntroductionDespite its ease of access and multifaceted health benefits, compared to pre-pregnancy, engagement in running decreases following childbirth (postpartum).
Megan L. James   +5 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Sıcak ve Soğuk Yolluk Sistemlerinin Karşılaştırılması

open access: yesDüzce Üniversitesi Bilim ve Teknoloji Dergisi, 2015
Plastik sektörü dünyada çok hızlı gelişen sektörlerin başında gelmektedir. Bu teknolojik gelişmeler ışığında hacim kalıplarında plastiklerin şekillendirilmesinde sıcak yolluk sisteminin önemini gittikçe arttırmıştır. Sıcak yolluk sisteminin önemli ölçüde
Arif Özkan, Turğut Öztürk
doaj  

Participation trends and performance analysis of Turkey’s long-distance runs between 2007-2017

open access: yesBaltic Journal of Health and Physical Activity, 2019
Background: Long-distance running events have gained more popularity worldwide over years. However, the number of participants to such events, age and sex distribution of participants may vary by country.
MELDA PELIN YARGIC   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Problems on track runners

open access: yesComputational Geometry, 2020
Consider the circle $C$ of length 1 and a circular arc $A$ of length $\ell\in (0,1)$. It is shown that there exists $k=k(\ell) \in \mathbb{N}$, and a schedule for $k$ runners along the circle with $k$ constant but distinct positive speeds so that at any time $t \geq 0$, at least one of the $k$ runners is not in $A$.
Adrian Dumitrescu, Csaba D. Tóth
openaire   +3 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

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