Results 21 to 30 of about 1,441,257 (261)
British Journal of Sports Medicine, 2019 Objective To investigate the association of running participation and the dose of running with the risk of all-cause, cardiovascular and cancer mortality. Design Systematic review and meta-analysis.
Ž. Pedišić +9 more
semanticscholar +1 more source
Theoretical Computer Science, 2011 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Maxime Crochemore +2 more
openaire +4 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Physiology and Pathophysiology in Ultra-Marathon Running
Frontiers in Physiology, 2018 In this overview, we summarize the findings of the literature with regards to physiology and pathophysiology of ultra-marathon running. The number of ultra-marathon races and the number of official finishers considerably increased in the last decades ...
B. Knechtle, P. Nikolaidis
semanticscholar +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Running-induced systemic Cathepsin B secretion is associated with memory function
Cell Metabolism, 2016 SUMMARY Peripheral processes that mediate beneficial effects of exercise on the brain remain sparsely explored. Here we show that a muscle secretory factor, Cathepsin B (CTSB) protein, is important for cognitive benefits of running.
H. Moon +11 more
semanticscholar +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Five-Loop Running of the QCD Coupling Constant. [PDF]
Physical Review Letters, 2016 We analytically compute the five-loop term in the beta function which governs the running of α_{s}-the quark-gluon coupling constant in QCD. The new term leads to a reduction of the theory uncertainty in α_{s} taken at the Z-boson scale as extracted from
P. Baikov, K. Chetyrkin, J. Kühn
semanticscholar +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging, 2020 30 Ecotoxicological hazard assessment relies on species effect data to estimate quantities such as the 31 predicted no-effect concentration. Whilst there is a concerted effort to quantify uncertainty in risk 32 assessments, the uncertainty due to inter-test
Y. Youngs +5 more
semanticscholar +1 more source