Results 41 to 50 of about 4,502,374 (286)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Running after Diphoton

open access: yes, 2016
A very plausible explanation for the recently observed diphoton excess at the 13 TeV LHC is a (pseudo)scalar with mass around 750 GeV, which couples to a gluon pair and to a photon pair through loops involving vector-like quarks (VLQs).
Gu, Jiayin, Liu, Zhen
core   +1 more source

Bulk versus brane running couplings [PDF]

open access: yes, 2001
A simplified higher dimensional Randall-Sundrum-like model in 6 dimensions is considered. It has been observed previously by Goldberger and Wise that in such a self-interacting scalar theory on the bulk with a conical singularity there is mixing of ...
A. A. Bytsenko   +15 more
core   +2 more sources

CLAVATA3 is a specific regulator of shoot and floral meristem development affecting the same processes as CLAVATA1 [PDF]

open access: yes, 1995
We have previously described the phenotype of Arabidopsis thaliana plants with mutations at the CLAVATA1 (CLV1) locus (Clark, S. E., Running, M. P. and Meyerowitz, E. M. (1993) Development 119, 397-418).
Clark, Steven M.   +2 more
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

CLAVATA1, a regulator of meristem and flower development in Arabidopsis [PDF]

open access: yes, 1993
We have investigated the effects on plant development of mutations in the Arabidopsis thaliana CLAVATA1 gene. In clavata1 plants, vegetative, inflorescence and floral meristems are all enlarged relative to wild type.
Clark, Steven E.   +2 more
core  

Running Boundary Condition

open access: yes, 2013
In this paper we argue that boundary condition may run with energy scale. As an illustrative example, we consider one-dimensional quantum mechanics for a spinless particle that freely propagates in the bulk yet interacts only at the origin.
Ohya, Satoshi   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

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