Results 61 to 70 of about 4,502,374 (286)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Modern Languages OpenBoth Indigenous researchers and Indigenous languages are under-represented in the emerging field of Artificial Intelligence (AI). Michael Running Wolf, founder of Indigenous in AI, the Lakota AI Code Camp, and the First Languages AI Reality project ...
Michael Running Wolf +1 more
doaj +1 more source
Biological aspects of salivary hormones in male half-marathon performance [PDF]
Archives of Biological Sciences, 2016 Physical effort is known to alter the blood levels of many hormones, but there are only a few studies about the biological changes of salivary hormones.
Radosavljević Branimir B. +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
International Journal of Computer Science in Sport, 2023 The Gothenburg Half Marathon is one of the world’s largest half marathon races with over 40 000 participants each year. In order to reduce the number of runners risking over-straining, injury, or collapse, we would like to provide runners with advice to ...
Johansson Moa +2 more
doaj +1 more source
Running-in wear modeling of honed surface for combustion engine cylinder liners [PDF]
, 2013 The texture change during running-in alters the performance and efficiency of a tribo-mechanical system. During mass production of cylinder liners, a final finishing stage known as ‘‘plateau honing’’ is commonly added to reduce the running-in wear ...
DEMIRCI, Ibrahim +3 more
core +6 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Journal of Advances in Modeling Earth SystemsOcean Alkalinity Enhancement (OAE) is emerging as a viable method for removing anthropogenic CO2 emissions from the atmosphere to mitigate climate change.
Kay Suselj +7 more
doaj +1 more source
Impact of water stress on physiological traits and yields of different varieties of spring wheat
Guan'gai paishui xuebao【Background】 Wheat is the second largest cereal crop after rice in China and is largely grown in arid and semiarid regions in the North. Understanding the impact of water stress on its growth and final yield is important to improve its water use ...
WANG Haosha, CAO Running, HUANG Xingfa
doaj +1 more source