Results 61 to 70 of about 3,821,420 (285)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

THE EFFECTS OF RUNNING ON YOUNG WOMEN'S WELLBEING [PDF]

open access: yesAnnals of the “Ştefan cel Mare” University: Physical Education and Sport Section - The Science and Art of Movement, 2019
Wellbeing is a holistic concept that describes a positive state of health and includes physical, social and psychological wellness. In addition to physical and functional follow-up goals, physical education and sports in university aims modeling the ...
Andreea – Gabriela Lazăr1
doaj  

Creating and Running Partnerships [PDF]

open access: yes, 2008
{Excerpt} A partnership is a formal or informal agreement between two or more partners to work together to achieve common aims. For instance, multilateral and bilateral agencies can compensate for abilities and resources that fall far short of ...
Serrat, Olivier
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Quantifying Marine Carbon Dioxide Removal via Alkalinity Enhancement Across Circulation Regimes Using ECCO‐Darwin and 1D Models

open access: yesJournal of Advances in Modeling Earth Systems
Ocean Alkalinity Enhancement (OAE) is emerging as a viable method for removing anthropogenic CO2 emissions from the atmosphere to mitigate climate change.
Kay Suselj   +7 more
doaj   +1 more source

Impact of water stress on physiological traits and yields of different varieties of spring wheat

open access: yesGuan'gai paishui xuebao
【Background】 Wheat is the second largest cereal crop after rice in China and is largely grown in arid and semiarid regions in the North. Understanding the impact of water stress on its growth and final yield is important to improve its water use ...
WANG Haosha, CAO Running, HUANG Xingfa
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Effects of an interdisciplinary method for training conductors [PDF]

open access: yes, 2009
This study investigated effects of a method designed to enhance novice conductors’ musical expressiveness, specificity, and comfort through incorporation of acting exercises.
Running, Donald J.
core   +1 more source

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