Results 81 to 90 of about 750,368 (294)

Subgroups of Foot-Ankle Movement Patterns Can Influence the Responsiveness to a Foot-Core Exercise Program: A Hierarchical Cluster Analysis

Frontiers in Bioengineering and Biotechnology, 2021
The purpose of this study is to identify homogenous subgroups of foot-ankle (FA) kinematic patterns among recreational runners and further investigate whether differences in baseline movement patterns can influence the mechanical responses to a foot-core
Ricky Watari, Eneida Y. Suda, João P. S. Santos, Alessandra B. Matias, Ulisses T. Taddei, Isabel C. N. Sacco   +5 more
doaj   +1 more source

Is There an Economical Running Technique? A Review of Modifiable Biomechanical Factors Affecting Running Economy

Sports Medicine, 2016
Running economy (RE) has a strong relationship with running performance, and modifiable running biomechanics are a determining factor of RE. The purposes of this review were to (1) examine the intrinsic and extrinsic modifiable biomechanical factors ...
I. Moore
semanticscholar   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Voluntary wheel running: patterns and physiological effects in mice

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2018
Exercise can prevent and improve the pathophysiology of diseases and promote healthy aging. Thus, understanding the mechanisms that regulate the beneficial effects of exercise may lead to the development of new strategies to enhance quality of life and ...
G. Manzanares, G. Brito-da-Silva, P. G. Gandra   +2 more
semanticscholar   +1 more source

EFFECTS OF A PROLONGED MAXIMAL RUN ON RUNNING ECONOMY AND RUNNING MECHANICS

Medicine and Science in Sports and Exercise, 1980
The purpose of this study was to document the effects of a prolonged (30 min) maximal run (PMR) on running economy (RE) and running mechanics in 16 male runners (mean VO2max = 59.0 +/- 4.5 ml.kg-1.min-1). After completing 60 min of treadmill accommodation, each subject performed two 10 min economy runs at 200 m.min-1.
Don W. Morgan, Gary S. Krahenbuhl, Fred D. Baldini, Philip E. Martin   +3 more
openaire   +3 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Quantifying Marine Carbon Dioxide Removal via Alkalinity Enhancement Across Circulation Regimes Using ECCO‐Darwin and 1D Models

Journal of Advances in Modeling Earth Systems
Ocean Alkalinity Enhancement (OAE) is emerging as a viable method for removing anthropogenic CO2 emissions from the atmosphere to mitigate climate change.
Kay Suselj, Dustin Carroll, Daniel Whitt, Bridget Samuels, Dimitris Menemenlis, Hong Zhang, Nate Beatty, Anna Savage   +7 more
doaj   +1 more source

Impact of water stress on physiological traits and yields of different varieties of spring wheat

Guan'gai paishui xuebao
【Background】 Wheat is the second largest cereal crop after rice in China and is largely grown in arid and semiarid regions in the North. Understanding the impact of water stress on its growth and final yield is important to improve its water use ...
WANG Haosha, CAO Running, HUANG Xingfa
doaj   +1 more source