Results 81 to 90 of about 3,821,420 (285)

The Virtual Runner Learning Game [PDF]

open access: yesInteraction Design and Architecture(s), 2014
A learning game has been developed which allows learners to study and learn about the significance of three important variables in human physiology (lactate, glycogen, and hydration) and their influence on sports performance during running.
Reinhold Behringer   +6 more
doaj  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Measuring the spectral running from cosmic microwave background and primordial black holes

open access: yes, 2018
We constrain the spectral running by combining cosmic microwave background (CMB) data, baryon acoustic oscillation (BAO) data and the constraint from primordial black holes (PBHs).
Huang, Qing-Guo, Li, Jun
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Evolution of world running record performances for men and women: physiological characteristics

open access: yesFrontiers in Physiology
Running world records (WRs) contain information about physiological characteristics that determine running performance. The progression of WRs over time encode the evolution of these characteristics.
Thorsten Emig, Guillaume Adam
doaj   +1 more source

Effective action and brane running

open access: yes, 2003
We address the renormalized effective action for a Randall-Sundrum brane running in 5d bulk space. The running behavior of the brane action is obtained by shifting the brane-position without changing the background and the fluctuations.
A. Lewandowski   +30 more
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Sex Difference in Triathlon Performance

open access: yesFrontiers in Physiology, 2019
This brief review investigates how sex influences triathlon performance. Performance time for both Olympic distance and Ironman distance triathlons, and physiological considerations are discussed for both elite and non-elite male and female triathletes ...
Romuald Lepers
doaj   +1 more source

Barefoot running improves economy at high intensities and peak treadmill velocity [PDF]

open access: yes, 2015
Aim: Barefoot running can improve running economy (RE) compared to shod running at low exercise intensities, but data is lacking for the higher intensities typical during many distance running competitions.
Barwood, Martin J.   +2 more
core  

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