Implementation of Drug‐Induced Rhabdomyolysis and Acute Kidney Injury in Microphysiological System
A modular Muscle–Kidney proximal tubule‐on‐a‐chip integrates 3D skeletal muscle and renal proximal tubule tissues to model drug‐induced rhabdomyolysis and acute kidney injury. The coculture system enables dynamic tissue interaction, functional contraction monitoring, and quantification of nephrotoxicity, revealing drug side effect‐induced metabolic ...
Jaesang Kim +4 more
wiley +1 more source
Cohort profile: trajectory of knee health in runners with and without heightened osteoarthritis risk (TRAIL) in Australia-prospective cohort study. [PDF]
De Oliveira Silva D +10 more
europepmc +1 more source
A programmable interpenetrating double‐network architecture, created via 3D‐TIPS printing and resin infusion, synergistically combines thermoplastic and thermosetting elastomers to balance structural rigidity and surface softness—crucial for paediatric laryngeal stents.
Elizabeth F. Maughan +14 more
wiley +1 more source
Relationships Between Hematological Variables and Bone Metabolism in Elite Female Trail Runners. [PDF]
Carrasco-Marginet M +6 more
europepmc +1 more source
Photonic Engineering Enables All‐Passive Upconversion Imaging with Low‐Intensity Near‐Infrared Light
A passive upconversion imaging system enables the observation of scenes illuminated by low‐intensity incoherent near‐infrared light from 750 to 930 nm, by converting it into the visible without the use of external power. The upconverter is enabled by triplet–triplet annihilation in a bulk heterojunction, with absorption enhanced by plasmonic resonators
Rabeeya Hamid +13 more
wiley +1 more source
Lessons from history for V ˙ O 2 max and the V ˙ O 2 plateau, part 1, 1920 - 1961: original concepts were based on discontinuous exercise protocols. [PDF]
Robergs RA +8 more
europepmc +1 more source
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj +21 more
wiley +1 more source
A review of uphill and downhill running: biomechanics, physiology and modulating factors. [PDF]
Lu Z +6 more
europepmc +1 more source
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria +7 more
wiley +1 more source
A Retrospective Study on the Antimicrobial Susceptibility Patterns of Elizabethkingia meningoseptica Specimens Among Adult Patients. [PDF]
Sahu R +4 more
europepmc +1 more source

