Results 91 to 100 of about 1,516,854 (381)
Spectral-element modeling of spontaneous earthquake rupture on rate and state faults: Effect of velocity-strengthening friction at shallow depths [PDF]
, 2008 We develop a spectral-element methodology (SEM) for simulating dynamic rupture on rate and state faults and use it to study how the rupture is affected by a shallow fault region of steady-state velocity-strengthening friction.
Ampuero, J.-P., Kaneko, Y., Lapusta, N.
core +2 more sources
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Source Mechanism and Rupture Directivity of the 18 May 2009 M_W 4.6 Inglewood, California, Earthquake [PDF]
, 2010 On 18 May 2009, an M_w 4.6 earthquake occurred beneath Inglewood, California, and was widely felt. Though source mechanism and its location suggest that the Newport–Inglewood fault (NIF) may be involved in generating the earthquake, rupture directivity ...
Chen, Yong +7 more
core
Rupture of multiple parallel molecular bonds under dynamic loading
, 2000 Biological adhesion often involves several pairs of specific receptor-ligand molecules. Using rate equations, we study theoretically the rupture of such multiple parallel bonds under dynamic loading assisted by thermal activation.
A. Albersdörfer +22 more
core +1 more source
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
Hidden multiple bond effects in dynamic force spectroscopy [PDF]
, 2012 In dynamic force spectroscopy, a (bio-)molecular complex is subjected to a steadily increasing force until the chemical bond breaks. Repeating the same experiment many times results in a broad distribution of rupture forces, whose quantitative ...
Abbou +50 more
core +2 more sources
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Uncommon case of abdominal pregnancy with spontaneous uterine rupture at 35 weeks
PAMJ Clinical Medicine, 2019 Abdominal pregnancy is a rare form of ectopic pregnancy and is frequently misdiagnosed. Here, we report a case of abdominal pregnancy with spontaneous uterine rupture of the cesarean-section scar at 35 weeks.
Abderrahim Siati +4 more
doaj +1 more source