Results 71 to 80 of about 564,230 (316)

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Sidewall Aneurysm Geometry as a Predictor of Rupture Risk Due to Associated Abnormal Hemodynamics

Frontiers in Neurology, 2019
Background: Hemodynamics play an important role in intracranial aneurysm (IA) initiation, growth, and rupture. Yet there remains no definitive quantitative analysis between abnormal hemodynamics and geometrical risk of IA development.Objective: The ...
Hailin Wan, Liang Ge, Lei Huang, Yeqing Jiang, Xiaochang Leng, Xiaoyuan Feng, Jianping Xiang, Xiaolong Zhang   +7 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Theoretical analysis of dynamic force spectroscopy experiments on ligand-receptor complexes [PDF]

, 2004
Raible M, Evstigneev M, Reimann P, Bartels FW, Ros R. Theoretical analysis of dynamic force spectroscopy experiments on ligand-receptor complexes. Journal of Biotechnology.
Evstigneev, Mykhaylo ; https://orcid.org/, Reimann, Peter, Bartels, FW, Ros, R, Raible, M   +4 more
core   +2 more sources

Finite Element Analysis of Air Gun Impact on Post-Keratoplasty Eye

Clinical Ophthalmology, 2020
Kanno Okamura, Asami Shimokawa, Rie Takahashi, Yusuke Saeki, Hiroaki Ozaki, Eiichi Uchio Department of Ophthalmology, Fukuoka University School of Medicine, Fukuoka, JapanCorrespondence: Eiichi UchioDepartment of Ophthalmology, Fukuoka University School ...
Okamura K, Shimokawa A, Takahashi R, Saeki Y, Ozaki H, Uchio E   +5 more
doaj  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Effet du trajet de chargement sur la déformation à rupture de matériaux métalliques [PDF]

, 2017
La simulation numérique par éléments finis est devenu un outil de développement incournable lors de l'élaboration de nouveaux systèmes technologiques dont on veut prédire le comportement élastique, plastique où à la rupture, quel que soit le chargement ...
Maheo, Laurent, Lafilé, Vincent, Penin, Arnaud, Grolleau, Vincent, Galpin, Bertrand   +4 more
core  

Rupture of Pectoralis Major Muscle in an Elderly Patient Receiving Long- Term Hemodialysis: Case Report and Literature Review [PDF]

, 2011
Total or near-total rupture of the pectoralis major muscle is rare. It has mainly occurred in male patients between 20- 40 years of age while performing weight-lifting.
HO, LI-CHUN;CHIANG, CHIH-KANG;HUANG, JENQ-WEN;HUNG, KUAN-YU;WU, KWAN-DUN, 何立鈞;姜至剛;黃政文;洪冠予;吳寬墩   +1 more
core   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Abstract Part III Prediction of Stress-Rupture Life of Glass/Epoxy Laminates in an Acidic Environment from Lamina Behavior [PDF]

, 2007
A means to predict remaining strength and life of composite components in harsh environments and under complex time-varying loadings can help to optimize designs and cut costs.
Prediction Of Stress-Rupture
core