Results 51 to 60 of about 263,484 (215)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
The comprehensive cohort model in a pilot trial in orthopaedic trauma [PDF]
, 2011 Background: The primary aim of this study was to provide an estimate of effect size for the functional outcome of operative versus non-operative treatment for patients with an acute rupture of the Achilles tendon using accelerated rehabilitation for ...
Matthew L Costa +11 more
core +2 more sources
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Delayed Therapy of Descending Aortic Coarctation Results in Anterior Cerebral Rupture: A Case Report
Frontiers in Pediatrics, 2021 Background: Coarctation of the aorta (CoA) is the congenital constriction or narrowing of the aortic lumen. These constrictions are primarily located in the descending aorta causing significant discrepancies in systolic blood pressures of the upper and ...
Kele Qin +5 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Majalah Kedokteran Bandung, 2016 Achilles tendon rupture is the most common ruptur of tendon in the lower limb despite being one of the toughest tendons. This rupture presents a complex problem to the treating surgeon especially if it is associated with tendon and soft tissue loss.
Hermawan Nagar Rasyid +2 more
doaj +1 more source
Frontiers in Reproductive Health, 2022 BackgroundOne of the most critical functions of the fetal membranes is to remain intact until the onset of labor to maintain the protective intrauterine fluid environment.
Tariku Abewa Abebe +3 more
doaj +1 more source
A Review of Creep Deformation and Rupture Mechanisms of Cr-Mo Alloy for the Development of Creep Damage Constitutive Equations under Lower Stress [PDF]
, 2013 This paper presents a review of creep deformation and rupture mechanisms of low Cr-Mo alloy for the development of its creep damage constitutive equations under lower stress.
Xu, Qiang +4 more
core
Nonlinear analysis of earthquake fault rupture interaction with historic masonry buildings [PDF]
, 2015 The response of historic masonry buildings to tectonic ground displacements is studied through analysis of a simple yet representative soil-foundation-masonry wall system.
Gazetas, George +2 more
core +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source