Results 61 to 70 of about 663,812 (314)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Teknik Rekonstruksi Turndown Flap Tendon Achilles dan Flap Fasiokutan Sural pada Ruptur Tendon Achilles yang Disertai Kerusakan Masif Jaringan Lunak: Laporan Kasus

Majalah Kedokteran Bandung, 2016
Achilles tendon rupture is the most common ruptur of tendon in the lower limb despite being one of the toughest tendons. This rupture presents a complex problem to the treating surgeon especially if it is associated with tendon and soft tissue loss.
Hermawan Nagar Rasyid, Andri Primadhi, Renaldi Prasetia   +2 more
doaj   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Case report of successful treatment of patient with ruptured celiac artery aneurysm

Frontiers in Surgery
Celiac artery aneurysms (САА) represent the fourth most common visceral artery aneurysm. Despite its rarity, CAA carries a definite risk of rupture and/or other serious complications, which can be fatal. The reported rupture risk varies in the scientific
I. A. Semenenko, I. A. Semenenko, V. A. Yumasheva, N. Alieva, N. V. Yasnopolskaya, V. M. Sysoev   +5 more
doaj   +1 more source

Relationship between strain localization and catastrophic rupture

, 2007
In order to explore a prior warning to catastrophic rupture of heterogeneous media, like rocks, the present study investigates the relationship between surface strain localization and catastrophic rupture.
汪海英, 白以龙, Hao, SW (reprint author), Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech, Beijing 100080, Peoples R China., 柯孚久, 夏蒙棼, 郝圣旺   +5 more
core   +1 more source

Cornual Pregnancy with Uterine Rupture: A Case Report

, 2021
Cornual pregnancy is a rare and hazardous form of ectopic pregnancy that causes massive hemorrhage and death. Presented herein is a 38-year-old female patient who was brought to our Emergency Department at 30 + 6 weeks of gestation for abdominal pain and
Jen Heng Pek, Vinodhini Elangovan
core   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Repair of Bilateral Quadriceps Tendon Rupture Using a Modified Knotless Suture Anchor and Internal Brace Technique: Surgical Technique and Case Report

Orthopaedic Surgery, 2022
Background Quadriceps tendon rupture (QTR) is a rare clinical condition often caused by indirect injury in healthy people. In addition, spontaneous and bilateral ruptures can occur in patients with predisposing factors, such as endocrine or rheumatic ...
Xiaoping Wang, Daoqiang Huang, Weili Feng, Weiwei Wu, Jian Huang, Luyao Chen, Yumin Tu   +6 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Sidewall Aneurysm Geometry as a Predictor of Rupture Risk Due to Associated Abnormal Hemodynamics

Frontiers in Neurology, 2019
Background: Hemodynamics play an important role in intracranial aneurysm (IA) initiation, growth, and rupture. Yet there remains no definitive quantitative analysis between abnormal hemodynamics and geometrical risk of IA development.Objective: The ...
Hailin Wan, Liang Ge, Lei Huang, Yeqing Jiang, Xiaochang Leng, Xiaoyuan Feng, Jianping Xiang, Xiaolong Zhang   +7 more
doaj   +1 more source