Results 61 to 70 of about 564,230 (316)

Delayed Therapy of Descending Aortic Coarctation Results in Anterior Cerebral Rupture: A Case Report

open access: yesFrontiers in Pediatrics, 2021
Background: Coarctation of the aorta (CoA) is the congenital constriction or narrowing of the aortic lumen. These constrictions are primarily located in the descending aorta causing significant discrepancies in systolic blood pressures of the upper and ...
Kele Qin   +5 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

A Review of Creep Deformation and Rupture Mechanisms of Cr-Mo Alloy for the Development of Creep Damage Constitutive Equations under Lower Stress [PDF]

open access: yes, 2013
This paper presents a review of creep deformation and rupture mechanisms of low Cr-Mo alloy for the development of its creep damage constitutive equations under lower stress.
Xu, Qiang   +4 more
core  

Teknik Rekonstruksi Turndown Flap Tendon Achilles dan Flap Fasiokutan Sural pada Ruptur Tendon Achilles yang Disertai Kerusakan Masif Jaringan Lunak: Laporan Kasus

open access: yesMajalah Kedokteran Bandung, 2016
Achilles tendon rupture is the most common ruptur of tendon in the lower limb despite being one of the toughest tendons. This rupture presents a complex problem to the treating surgeon especially if it is associated with tendon and soft tissue loss.
Hermawan Nagar Rasyid   +2 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Case report of successful treatment of patient with ruptured celiac artery aneurysm

open access: yesFrontiers in Surgery
Celiac artery aneurysms (САА) represent the fourth most common visceral artery aneurysm. Despite its rarity, CAA carries a definite risk of rupture and/or other serious complications, which can be fatal. The reported rupture risk varies in the scientific
I. A. Semenenko   +5 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Creep-Rupture Study of Annealed Zircaloy 4: Stress and Temperature Effects [PDF]

open access: yes, 2005
Zircaloys are widely used as fuel rod cladding in light water reactors (LWRs) because of their low cross-section for absorption of thermal neutrons. Currently, the United States does not permit reprocessing of spent fuel so the primary barrier for the ...
Marple, Brian Wesley
core  

Hydrocele Rupture during Sexual Intercourse: a Case Report and Review of the Literature [PDF]

open access: yes, 2020
Hydrocele rupture is a rarely seen situation in clinical practice. Due to the limited number of cases in the literature, management of hydrocele rupture is controversial.
Deniz Bolat   +3 more
core   +1 more source

Repair of Bilateral Quadriceps Tendon Rupture Using a Modified Knotless Suture Anchor and Internal Brace Technique: Surgical Technique and Case Report

open access: yesOrthopaedic Surgery, 2022
Background Quadriceps tendon rupture (QTR) is a rare clinical condition often caused by indirect injury in healthy people. In addition, spontaneous and bilateral ruptures can occur in patients with predisposing factors, such as endocrine or rheumatic ...
Xiaoping Wang   +6 more
doaj   +1 more source

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