Results 31 to 40 of about 508,787 (299)

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Spontaneous uterine rupture in unscarred uterus in a low resource setting in India: A case series

Bangabandhu Sheikh Mujib Medical University Journal, 2023
Uterine rupture, a critical event during childbirth, poses significant challenges in familial and societal contexts. Despite concerted efforts to prevent such occurrences, inevitabilities arise, placing immense burdens on emergency healthcare teams ...
Pushpal Chowdhury
doaj  

Captured Rotator Cuff: A Poor Prognostic Factor in Rotator Cuff Repair [PDF]

Revista Brasileira de Ortopedia
Objective To describe a new presentation of tears and retears of the rotator cuff, which we denominate captured rotator cuff (CRC). We also aim to evaluate it clinically and through images.
Flavio de Oliveira França, José Márcio Alves Freitas, Ricardo Palombini Medeiros, Romero Ruan Cartaxo de Queiroga, Tiago Prause Nunes, Glaydson Gomes Godinho   +5 more
doaj   +3 more sources

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Hepatic Hydatid Disease Causing Gastric Ulcer as a Rare Complication

대한영상의학회지, 2019
Hydatid disease in humans is a parasitic disease typically caused by the larvae of Echinococcus granulosus. Although the disease can occur in any body part, it most frequently affects the liver.
Eunae Cho, Sang Soo Shin, Ga Eon Kim
doaj   +1 more source

Importance of inflammation in arteriosclerotic plaque destabilization and rupture [PDF]

Vojnosanitetski Pregled, 2005
Introduction. Although Rudolf Virchow considered arteriosclerosis an inflammatory disease in his book Cellular Pathology published in 1858, the opinion that it was a degenerative arterial disease as a civilization disease prevailed.
Tatić Vujadin, Kanjuh Vladimir, Rafajlovski Saša I., Kostić Kristina, Šuščević Dušan   +4 more
doaj   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Extensor mechanism ruptures

EFORT Open Reviews, 2022
Native patellar tendon injuries are seen in younger patients compared to quadriceps tendon ruptures. Up to a third of the patients may have local (antecedent tendinopathy and cortisone injections) or systemic risk factors (obesity, diabetes, hyperparathyroidism, chronic renal failure, fluoroquinolone or statin use) of injury, these are more ...
Reha N Tandogan, Esref Terzi, Enrique Gomez-Barrena, Bruno Violante, Asim Kayaalp   +4 more
openaire   +4 more sources

Flow Diverter Treatment of Ruptured Basilar Artery Perforator Aneurysms [PDF]

, 2022
Samer Elsheikh, Markus Möhlenbruch, Fatih Şeker, Ansgar Berlis, Christoph J. Maurer, Naci Koçer, Ala Jamous, Daniel Behme, Christian Taschner, Horst Urbach, Stephan Meckel   +10 more
openalex   +1 more source

SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas, Pablo Iruzubieta, Alberto Damborenea, Laura Pérez‐Fernández, Inmaculada Azorín, Juan Carlos Jiménez García, Ana Töpf, Pilar Martí, Lorena Fores‐Toribio, María Manterola, Rosana Blanco‐Mañez, Oihane Pikatza‐Menoio, Sonia Alonso‐Martín, Volker Straub, Aitziber L. Cortajarena, Adolfo López de Munain, David De Sancho, Lorea Blázquez, Juan J. Vilchez   +18 more
wiley   +1 more source