Results 121 to 130 of about 535,703 (253)
Molecular Glue Degraders in Early Development for Cancer Therapy
Medicinal Research Reviews, EarlyView.ABSTRACT Molecular glue degraders are an emerging class of small molecule allosteric modulators that induce or stabilize protein‐protein interactions, enabling targeted degradation of previously intractable proteins. By redirecting E3 ligases to recognize neosubstrates, proteins that are not typically recognized by a specific E3 ubiquitin ligase, they ...
E. Sila Ozdemir +4 more
wiley +1 more source
Ruth Weinman Herndon childhood photograph
, 1909 Glass plate negative of Ruth Weinman Herndon holding a doll. The little girl is wearing a long dress with a lace hem and yoke, dark shoes, and a necklace. She is seated on an armchair and is holding a doll with both hands.
core +1 more source
Frailty and Recovery Following Free Flap Reconstruction in Head and Neck Cancer: A Systematic Review
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective To review the impact of frailty on various outcomes in geriatric head and neck cancer (HNC) patients undergoing microvascular free flap reconstruction (MFFR). Data Sources MEDLINE, Embase, and World of Science. Review Methods Following PRISMA guidelines, two independent reviewers performed a systematic review of MEDLINE, Embase, and ...
Anvitha R. Metpally +7 more
wiley +1 more source
Oikos, EarlyView.Many key ecosystem functions are affected by plant roots and their traits. However, understanding of the patterns in, and drivers of, root traits lags far behind equivalent knowledge of above‐ground tissues, particularly in boreal old growth forests. We surveyed community‐level root traits across 11 old growth forests spanning a wide latitudinal range ...
Naomi Vöhringer +4 more
wiley +1 more source
Pediatric Anesthesia, EarlyView.ABSTRACT Background Trauma is one of the leading causes of death in children. Trauma patients have been demonstrated to require significant resources, including operating room time. We aimed to describe the characteristics and patterns of access to surgery and outcomes of pediatric major trauma patients at The Hospital for Sick Children.
Ruth Bird +3 more
wiley +1 more source
Silverman-Anderson Score and Downes Score for Assessing Respiratory Distress in Newborns
JLUMHSOBJECTIVE: To compare the effectiveness of the Silverman-Anderson and Downes scoring systems in predicting respiratory distress in newborns admitted to pediatric nursery.
Abdul Salam Memon +5 more
doaj +1 more source
Contrastive Characterization in Ruth 1:6–22: Three Ways to Return from Exile
Old Testament Essays, 2019 By using the narrative device of contrastive characterization, the author of Ruth demonstrates three return-from-exile scenarios that act as a model for the audience. Orpah served as Ruth’s foil and represents a return to the pagan culture.
Timothy L Decker
doaj
Percutaneous peripheral nerve stimulation as an ancillary treatment following nerve repair surgery
PM&R, EarlyView.Abstract Background Neuropathic pain after peripheral nerve injury severely degrades quality of life. Peripheral nerve stimulation (PN‐Stim) is cleared by the U.S, Food and Drug Administration for the treatment of acute and chronic pain. This broad indication supports its potential use at the time of peripheral nerve repair in patients reporting ...
Shyam Maisuria +4 more
wiley +1 more source
PLANTS, PEOPLE, PLANET, EarlyView.DNA fingerprinting is becoming the standard measurement procedure in crop adoption studies in the Global South, yet the lack of systematic and intentional sampling regarding which farmer to go to the plot with may bias results from these methods. We introduce a methodological innovation, Sampling for Socially Inclusive Adoption Studies (SSAS), to offer
Yoselyn Hernandez Chaves +12 more
wiley +1 more source