Results 201 to 210 of about 136,793 (258)

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

Dual Active Forms of Milstein's Catalyst for Ester Hydrogenation. [PDF]

Organometallics
Ye H, Keith JM, Chianese AR.
europepmc   +1 more source

Targeting the KAT7/H3K14ac/RAC2 Axis Mediates OXPHOS to Promote Stemness Maintenance and Malignancy in Glioblastoma

Advanced Science, EarlyView.
SOX2 upregulates KAT7 in glioma stem cells, where KAT7 deposits H3K14 acetylation at the RAC2 promoter to activate RAC2 transcription. RAC2‐GTP subsequently promotes PAK1/2/3 phosphorylation, increasing tricarboxylic acid cycle flux and mitochondrial respiration to support glioblastoma malignancy.
Jilong Liu, Yanfei Sun, Yuehua Zhu, Guangjing Mu, Jiazheng Wang, Liangliang Wang, Feihu Zhao, Zhimin Zhao, Jian Wang, Ying He, Zheng Jiang, Xingang Li, Mingzhi Han, Bin Huang   +13 more
wiley   +1 more source

Ruthenium Nitrosyl Complexes with Bidentate Heterocycles and Chloride Ligands: Synthesis and Photorelease of NO. [PDF]

Int J Mol Sci
Brovko AO, Yakovlev IA, Kuratieva NV, Sheven DG, Kostin GA.   +4 more
europepmc   +1 more source

Probabilistic Computing via Gate‐Tunable Random Telegraph Noise

Advanced Science, EarlyView.
Intrinsic random telegraph noise in metal–oxide–semiconductor field‐effect transistors is harnessed to create gate‐tunable probabilistic bits. By modulating carrier‐trapping dynamics, the device produces stochastic binary outputs with a continuous bias‐to‐probability transfer.
Gyungwon Yun, Jin Pyo Kang, Ho‐Sung Lee, Ik‐Hyeon Jeon, Ki‐Ju Park, Won‐Ju Cho, Seung‐heon Chris Baek, Joo‐Hyung Chae, Hamin Park   +8 more
wiley   +1 more source

A Ruthenium-(Ph-BPE) Catalyst for Asymmetric Alkynylation of Fluoral: Enantioselection From 1 of 12 Fluxional Stereogenic-at-Ruthenium Complexes. [PDF]

Angew Chem Int Ed Engl
Shen W, Höthker S, Hayter CE, Bowers NK, Pellegrini A, Grimme S, Krische MJ.   +6 more
europepmc   +1 more source

High‐Throughput Screening for Accelerated Oxide Glass Discovery

Advanced Science, EarlyView.
A high‐throughput screening platform is presented that allows for accelerating laboratory glass synthesis by a factor of 102, using multicomponent stereolithographic printing. Automatic sample evaluation is achieved via Raman spectroscopy and similarity analysis without any sample preparation.
Igor Seibel‐Geraschenko, Josef Slowik, Franziska Scheffler, Alexis Duval, N. M. Anoop Krishnan, Lothar Wondraczek   +5 more
wiley   +1 more source

Intelligent Programmable Membrane Nanosponge for Early Virus Blocking

Advanced Science, EarlyView.
A smart programmable nanosponge (ACNPs) displays high‐density viral receptors on its membrane and encapsulates fusion inhibitors to capture virions at the infection source through competitive binding and blocks their entry through protease inhibition for ultra‐early cascade interception. This modular, mucus‐penetrating platform shifts antiviral defence
Ze Chen, Zhuojun He, Huimin Guo, Min Shi, Ruijing Liang, Lanlan Liu, Yeneng Dai, Qi Zhao, Ke Liu, Yang Zhou, Yang Zhang, Jian Ren, Bin Ju, Quan Fang, Zhaozhen Li, Pengfei Zhao, Mingbin Zheng, Lintao Cai   +17 more
wiley   +1 more source

Influence of Ru Content on Defect Formation and Electrocatalytic Activity of Au‐Pd‐Pt‐Ru Compositionally Complex Solid Solution Thin Films for the Hydrogen Evolution Reaction

Advanced Science, EarlyView.
Transmission electron microscopy reveals that the formation of planar defects in Au–Pd–Pt–Ru CCSS thin films depends on Ru content, which in turn influences hydrogen evolution reaction electrocatalytic activity. As the Ru content increases, the density of nanotwins initially rises; with further Ru addition, stacking faults form.
Miran Joo, Huixin Xiu, Sabrina Baha, Ridha Zerdoumi, Ningyan Cheng, Christoph Somsen, Yujiao Li, Aleksander Kostka, Wolfgang Schuhmann, Alfred Ludwig, Christina Scheu   +10 more
wiley   +1 more source

Effects of Increased Ligand Fields of the Second- and Third-Row Transition Metals on the Preferred Structures of Sandwich Compounds of Stoichiometry C₁₂H₁₂M. [PDF]

Organometallics
Liu Y, Chen H, Luo J, Li H, Fan Z, Fan Q, King RB, Schaefer HF.   +7 more
europepmc   +1 more source