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Ruthenium complexes as antimicrobial agents
This review surveys the on-going search for ruthenium complexes that are potentially toxic to bacteria but relatively non-toxic to eukaryotic cells.
Fangfei Li +2 more
exaly +7 more sources
Metal Ruthenium Complexes Treat Spinal Cord Injury By Alleviating Oxidative Stress Through Interaction With Antioxidant 1 Copper Chaperone Protein [PDF]
Oxidative stress is a major factor affecting spinal cord injury (SCI) prognosis. A ruthenium metal complex can aid in treating SCI by scavenging reactive oxygen species via a protein‐regulated mechanism to alleviate oxidative stress.
Juanjuan Li +10 more
doaj +2 more sources
Special Issue on Ruthenium Complexes
The organic chemistry of ruthenium has been one of the most vigorously growing research areas over the past decades. Considerable effort has been extended towards the design and application of a broad series of ruthenium complexes, which culminated with ...
Ileana Dragutan +2 more
doaj +3 more sources
Functionalisation of bolaamphiphiles with mononuclear bis(2,2'-bipyridyl)ruthenium(II) complexes for application in self assembled monolayers [PDF]
A novel ruthenium(II) polypyridyl complex connected competently to a bolaamphiphile, containing amide linkages to provide rigidity via hydrogen bonding in the monolayer, has been prepared.
Anderson +48 more
core +11 more sources
Metal complexes have been used to treat cancer since the discovery of cisplatin and its interaction with DNA in the 1960’s. Facing the resistance mechanisms against platinum salts and their side effects, safer therapeutic approaches have been sought ...
Christian Gaiddon +9 more
doaj +1 more source
Synthesis, spectral, dna binding and cleavage properties of ruthenium(II) Schiff base complexes containing PPh3/AsPh3 as co-ligands [PDF]
A dihydroxybenzaldehyde Schiff base ligands (L1-L3) and its ruthenium(II) complexes, have been synthesized and characterized on the basis of elemental analysis, 1H, 13C, 31P NMR, mass spectra, UV-vis and IR spectra.
Sathiyaraj Subbaiyan +2 more
doaj +1 more source
Ruthenium(II) dimethyl sulphoxide based complexes: A potent inducer of apoptosis
Ruthenium (Ru) Dimethylsulphoxide complexes have appeared as a prominent compound among the potential metal-based drug for the cure of cancer. Cancer is marked with the uncontrolled proliferative activity that can be treated with apoptosis inducers ...
Sunita Khatkar +7 more
doaj +1 more source
Biological Activities of Ruthenium NHC Complexes: An Update
Ruthenium N-heterocyclic carbene (NHC) complexes have unique physico-chemical properties as catalysts and a huge potential in medicinal chemistry and pharmacology, exhibiting a variety of notable biological activities.
Alessia Catalano +6 more
doaj +1 more source
In these studies, we investigated the antioxidant activity of three ruthenium cyclopentadienyl complexes bearing different imidato ligands: (η5-cyclopentadienyl)Ru(CO)2-N-methoxysuccinimidato (1), (η5-cyclopentadienyl)Ru(CO)2-N-ethoxysuccinimidato (2 ...
Michał Juszczak +4 more
doaj +1 more source
A new series of pincer type ruthenium(II) Schiff base complexes namely [Ru(CO)(PPh3)2(L1‒6)] (1–6) (where, L1‒6 = NOO ‒ donors of tri-dentate ligands) have been synthesized from ruthenium precursor such as [RuHCl(CO)(PPh3)3] containing tri-dentate ...
Premkumar Muniyappan +2 more
doaj +1 more source

