Organometallic half-sandwich iridium anticancer complexes [PDF]
The low-spin 5d6 IrIII organometallic half-sandwich complexes [(η5-Cpx)Ir(XY)Cl]0/+, Cpx = Cp*, tetramethyl(phenyl)cyclopentadienyl (Cpxph), or tetramethyl(biphenyl)cyclopentadienyl (Cpxbiph), XY = 1,10-phenanthroline (4−6), 2,2′-bipyridine (7−9 ...
Liu, Zhe +34 more
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Ruthenium complexes currently represent a perspective subject of investigation in terms of potential anticancer therapeutics. Eight novel octahedral ruthenium(II) complexes are the subject of this article.
Martin Schoeller +8 more
doaj +1 more source
Photochemical ligand ejection from non-sterically promoted Ru(ii)bis(diimine) 4,4′-bi-1,2,3-triazolyl complexes [PDF]
Complexes of the form [Ru(diimine)2(btz)]2+ (btz = 1,1′-dibenzyl-4,4′-bi-1,2,3-triazolyl) are observed to undergo photochemical ejection of the btz ligand in the absence of any promotion through steric congestion to generate cis-bis(solvent) complexes ...
Sinopoli, Alessandro +6 more
core +1 more source
Synthesis and characterisation of Ruthenium(II) tris(heteroleptic) complexes containing a triazole ligand [PDF]
The synthesis, spectroscopic and electrochemical characterisation of Ru(II) tris(heteroleptic) mononuclear and dinuclear complexes are described. Special attention is paid to the introduction of a triazole ligand to the metal sphere.
Mulhern, Declan
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Dinuclear thiolato-bridged arene ruthenium complexes: from reaction conditions and mechanism to synthesis of new complexes [PDF]
Several dinuclear thiophenolato-bridged arene ruthenium complexes [(η(6)-p-MeC(6)H(4)Pr(i))(2)Ru(2)(μ(2)-SC(6)H(4)-R)(3)](+) (R = H, NO(2), F) could so far only be obtained in fair yields using the synthetic route established in the early 2000s.
Ninova, Silviya +5 more
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Five heteroleptic ruthenium(II) polypyridyl complexes [Ru(FL1)(dcbpy)(NCS)] (1), [Ru(FL2)(dcbpy)(NCS)] (2), [Ru(FL3)(dcbpy)(NCS)] (3), [Ru(FL1)(dcbpy)(NCS)] (4), and [Ru(FL5)(dcbpy)(NCS)] (5) (where FL1 = aniline dithiocarbamate, FL2 = p-anisidine ...
Zintle Fudo +2 more
doaj +1 more source
Functionalization of osmium arene anticancer complexes with (poly)arginine : effect on cellular uptake, internalization, and cytotoxicity [PDF]
Attaching peptides to metallodrugs may result in improved biological properties of the complexes. The potential use of cell penetrating peptides (CPPs) as cell delivery vectors is attractive, since directed cell uptake of (metallo)drugs remains a major ...
Rijt, Sabine H. van +7 more
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A series of ruthenium(ii) complexes with N-heterocyclic carbene (NHC) ligands of the general type (arene)(NHC)Ru(ii)X2 (where X = halide) (3a–3d) were synthesized and characterized in order to compare their antibacterial activities with benzimidazolium ...
Jawhari Ahmed Hussain +8 more
doaj +1 more source
Somatostatin subtype-2 receptor-targeted metal-based anticancer complexes [PDF]
Conjugates of a dicarba analogue of octreotide, a potent somatostatin agonist whose receptors are overexpressed on tumor cells, with [PtCl 2(dap)] (dap = 1-(carboxylic acid)-1,2-diaminoethane) (3), [(η 6-bip)Os(4-CO 2-pico)Cl] (bip = biphenyl, pico ...
González, Carlos A. +24 more
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Probing ground and excited state properties of ruthenium (II) and osmium (II) polypyridyl complexes [PDF]
The area of ruthenium(H) and osmium(H) polypyridyl chemistry has been the subject of intense investigation over the last half century. In chapter 1, topics relevant to the studies presented in this thesis are introduced.
Browne, Wesley R.
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