Results 21 to 30 of about 99,963 (359)

Dicarba-closo-dodecarborane-containing half-sandwich complexes of ruthenium, osmium, rhodium and iridium : biological relevance and synthetic strategies [PDF]

, 2012
This review describes how the incorporation of dicarba-closo-dodecarboranes into half-sandwich complexes of ruthenium, osmium, rhodium and iridium might lead to the development of a new class of compounds with applications in medicine. Such a combination
Barry, Nicolas P. E., Sadler, P. J.
core   +1 more source

Apoptotic Properties of Rutheinum Complexes on Different Type of Cancer Cell Lines

Proceedings, 2018
Among chemotherapeutic agents, cisplatin and the other platinum-based drugs have occupied for 35 years an enviable position. The limitations of platinum-based drugs, dose dependent side effects and development of drug resistance mechanisms, have boosted ...
Hafize Seda Vatansever, Hilal Kabadayı, Mehmet Korkmaz, Feyzan Özdal-Kurt, Serdar Batıkan Kavukcu, Hayati Türkmen   +5 more
doaj   +1 more source

Electrochemical Detection of Tadalafil at Glassy Carbon Electrodes Modified with Ruthenium(II) Complex

International Journal of Electrochemical Science, 2020
Ruthenium complexes are well known for their electrochemical activity, which could be attributed to the presence of stable ruthenium complexes with divalent ruthenium center, Ru2+.
Eyad S.M. Abu-Nameh, Naela Al Absi, Mohammad A. Al-Wahish, Hamdallah A. Hodali, Mohammad F. Khanfar   +4 more
doaj   +1 more source

Current applications and future potential for bioinorganic chemistry in the development of anticancer drugs [PDF]

, 2009
This review illustrates notable recent progress in the field of medicinal bioinorganic chemistry as many new approaches to the design of innovative metal-based anticancer drugs are emerging.
Aird, Ang, Barnard, Barnes, Bednarski, Bergamo, Bergamo, Bindoli, Campone, Chatterjee, Che, Chen, Chen, Chen, Chen, Choy, Clarke, Cordier, Desoize, Detty, Dougan, Ernst, Failes, Farrer, Feazell, Fricker, Gabbiani, Gunatilleke, Hall, Hambley, Hamelers, Henderson, Hillard, Hotze, Hotze, Jakupec, Jakupec, Junicke, Kelland, Kostenich, Kostova, Kostrhunova, Li, Mackay, Mackay, Meggers, Mosi, Nguyen, Noor, Oliveira, Ott, Ott, Ott, Peacock, Peacock, Peacock, Peter J. Sadler, Petzold, Petzold, Powis, Rademaker-Lakhai, Sabine H. van Rijt, Sadler, Saggioro, Sergeant, Sessler, Sharman, Shaw, Sherman, Smalley, Storr, Urig, van Rijt, Vessieres, Wang, Wang   +75 more
core   +1 more source

Latent olefin metathesis catalysts [PDF]

, 2009
Olefin metathesis is a versatile synthetic tool for the redistribution of alkylidene fragments at carbon-carbon double bonds. This field, and more specifically the development of task-specific, latent catalysts, attracts emerging industrial and academic ...
Drozdzak, Renata, Lozano Vila, Ana, Monsaert, Stijn, Van Der Voort, Pascal, Verpoort, Francis   +4 more
core   +2 more sources

Antitumor Activity of Ruthenium(II) Terpyridine Complexes towards Colon Cancer Cells In Vitro and In Vivo

Molecules, 2020
Ruthenium complexes have attracted considerable interest as potential antitumor agents. Therefore, antitumor activity and systemic toxicity of ruthenium(II) terpyridine complexes were evaluated in heterotopic mouse colon carcinoma.
Maja Savic, Aleksandar Arsenijevic, Jelena Milovanovic, Bojana Stojanovic, Vesna Stankovic, Ana Rilak Simovic, Dejan Lazic, Nebojsa Arsenijevic, Marija Milovanovic   +8 more
doaj   +1 more source

The contrasting activity of iodido versus chlorido ruthenium and osmium arene azo- and imino-pyridine anticancer complexes : control of cell selectivity, cross-resistance, p53 dependence, and apoptosis pathway [PDF]

, 2013
Organometallic half-sandwich complexes [M(p-cymene)(azo/imino-pyridine)X]+ where M = RuII or OsII and X ═ Cl or I, exhibit potent antiproliferative activity toward a range of cancer cells.
Romero-Canelón, Isolda, Sadler, P. J., Salassa, Luca   +2 more
core   +1 more source

Bipyridine Ruthenium(II) Complexes with Halogen-Substituted Salicylates: Synthesis, Crystal Structure, and Biological Activity

Molecules, 2023
Ruthenium complexes currently represent a perspective subject of investigation in terms of potential anticancer therapeutics. Eight novel octahedral ruthenium(II) complexes are the subject of this article.
Martin Schoeller, Milan Piroš, Miroslava Litecká, Katarína Koňariková, Flóra Jozefíková, Alexandra Šagátová, Eva Zahradníková, Jindra Valentová, Ján Moncol   +8 more
doaj   +1 more source

MECHANISTIC STUDY OF A RUTHENIUM HYDRIDE COMPLEX OF TYPE [RuH(CO)(N-N)(PR3)2]+ AS CATALYST PRECURSOR FOR THE HYDROFORMYLATION REACTION OF 1-HEXENE [PDF]

, 2016
Indexación: Web of Science; Scopus; Scielo.The catalytic activity of systems of type [RuH(CO)(N-N)(PR3)(2)](+) was evaluated in the hydroformylation reaction of 1-hexene. The observed activity is explained through a reaction mechanism on the basis of the
Cardenas-Jiron, G, Lopez, R, Moya, SA, Perez, C, Yanez, M, Zuniga, C   +5 more
core   +1 more source

New trends for metal complexes with anticancer activity [PDF]

, 2008
Medicinal inorganic chemistry can exploit the unique properties of metal ions for the design of new drugs. This has, for instance, led to the clinical application of chemotherapeutic agents for cancer treatment, such as cisplatin. The use of cisplatin is,
Ang, Ang, Barnard, Barnes, Bednarski, Bergamo, Bregman, Calderone, Casini, Debreczeni, Dixon, Dyson, Failes, Feazell, Guo, Habtemariam, Hall, Hambley, Hannon, Harris, Heringova, Hillard, Hotze, James, Jung, Komeda, Liu, Lutterman, MacDiarmid, Mackay, Mackay, McNae, Meggers, Milacic, Noor, Oleksi, Orvig, Ott, Pascu, Peacock, Peter J Sadler, Pieter CA Bruijnincx, Reed, Schatzschneider, Schlawe, Scolaro, Smalley, Sun, Thompson, Timerbaev, Urig, Urig, van Zutphen, Wang, Weidt, Yan, Yang   +56 more
core   +1 more source