Results 11 to 20 of about 40,348 (311)

Applications of Ruthenium Complexes Covalently Linked to Nucleic Acid Derivatives

Molecules, 2018
Oligonucleotides are biopolymers that can be easily modified at various locations. Thereby, the attachment of metal complexes to nucleic acid derivatives has emerged as a common pathway to improve the understanding of biological processes or to steer ...
Marie Flamme, Emma Clarke, Gilles Gasser, Marcel Hollenstein   +3 more
doaj   +2 more sources

Unusual DNA binding modes for metal anticancer complexes [PDF]

, 2009
DNA is believed to be the primary target for many metal-based drugs. For example, platinum-based anticancer drugs can form specific lesions on DNA that induce apoptosis.
Pizarro, Ana M., Sadler, P. J.
core   +1 more source

The Influence of Some Axial Ligands on Ruthenium–Phthalocyanine Complexes: Chemical, Photochemical, and Photobiological Properties

Frontiers in Molecular Biosciences, 2021
This work presents a new procedure to synthesize ruthenium–phthalocyanine complexes and uses diverse spectroscopic techniques to characterize trans-[RuCl(Pc)DMSO] (I) (Pc = phthalocyanine) and trans-[Ru(Pc)(4-ampy)2] (II) (4-ampy = 4-aminopyridine).
Tássia Joi Martins, Tássia Joi Martins, Laisa Bonafim Negri, Laisa Bonafim Negri, Laisa Bonafim Negri, Laena Pernomian, Laena Pernomian, Kelson do Carmo Freitas Faial, Congcong Xue, Regina N. Akhimie, Michael R. Hamblin, Claudia Turro, Roberto S. da Silva, Roberto S. da Silva, Roberto S. da Silva, Roberto S. da Silva   +15 more
doaj   +1 more source

3-Methylindole-Based Tripodal Tetraphosphine Ruthenium Complexes in N2 Coordination and Reduction and Formic Acid Dehydrogenation

Inorganics, 2017
The ruthenium(II) complexes RuCl2L1H, RuCl2L1CF3, RuCl2L1OMe and RuCl2L2H were synthesized from [Ru(η6-benzene)Cl(μ-Cl)]2 and the corresponding tripodal tris-3-methylindolephosphine-based ligands L1H, L1CF3, L1OMe, and L2H.
Fenna F. van de Watering, Nicol Heijtbrink, Jarl Ivar van der Vlugt, Wojciech I. Dzik, Bas de Bruin, Joost N. H. Reek   +5 more
doaj   +1 more source

Preparation of pyranylidene complexes of ruthenium

Dalton Transactions, 2015
Dimerization of alkylpropiolate on the half-sandwich fragment [Ru(η5-C5H5)(PPh3){P(OMe)3}]+ affords pyranylidene derivatives.
ALBERTIN, Gabriele, ANTONIUTTI, Stefano, BORTOLUZZI, Marco, BOTTER, ALESSANDRA, J. Castro   +4 more
openaire   +4 more sources

The contrasting activity of iodido versus chlorido ruthenium and osmium arene azo- and imino-pyridine anticancer complexes : control of cell selectivity, cross-resistance, p53 dependence, and apoptosis pathway [PDF]

, 2013
Organometallic half-sandwich complexes [M(p-cymene)(azo/imino-pyridine)X]+ where M = RuII or OsII and X ═ Cl or I, exhibit potent antiproliferative activity toward a range of cancer cells.
Sadler, P. J., Romero-Canelón, Isolda, Salassa, Luca   +2 more
core   +1 more source

Chiral Cyclopentadienyl Ruthenium Complexes as Versatile Catalysts for Enantioselective Transformations

CHIMIA, 2017
Ruthenium complexes, in particular cyclopentadienyl ruthenium (??) derivatives, catalyze a vast number of transformations in the field of homogenous catalysis.
David Kossler, Nicolai Cramer
doaj   +1 more source

Ruthenium(II)–Cyclopentadienyl-Derived Complexes as New Emerging Anti-Colorectal Cancer Drugs

Pharmaceutics, 2022
Colorectal cancer (CRC) is one of the most common malignancies and one of the leading causes of cancer-related death worldwide, urging the need for new and more efficient therapeutic approaches. Ruthenium complexes have emerged as attractive alternatives
Catarina Teixeira-Guedes, Ana Rita Brás, Ricardo G. Teixeira, Andreia Valente, Ana Preto   +4 more
doaj   +1 more source

Ruthenium porphyrin-ß-cyclodextrin complexes as supramolecular enzyme models for regioselective cleavage of carotenoids [PDF]

, 2006
All naturally occurring vitamin A derives from enzymatic oxidative cleavage of β,β-carotene or other carotenoids with pro-vitamin A activity. Two metabolic pathways of β,β-carotene to retinal (vitamin A aldehyde) have been proposed: the central cleavage ...
Wang, Hao
core   +1 more source

Rationally Designed Ruthenium Complexes for Breast Cancer Therapy

Molecules, 2020
Since the discovery of the anticancer potential of ruthenium-based complexes, several species were reported as promising candidates for the treatment of breast cancer, which accounts for the greatest number of new cases in women every year worldwide ...
Golara Golbaghi, Annie Castonguay
doaj   +1 more source