Results 141 to 150 of about 982,093 (257)

Antibacterial activity and DNA interaction of triazine iron and ruthenium complexes: spectroscopic, voltammetric and theoretical studies. [PDF]

RSC Adv, 2023
Albaqami FF, Sahib AS, Alharthy KM, Altharawi A, Alshahrani MY, Alshahrani MY, Jawad MA, Suliman M, Ahmad I.   +8 more
europepmc   +1 more source

Tumor‐Derived Exosomal circAP2B1 Induces M2 Macrophage Polarization by Enhancing Mitochondrial Homeostasis to Promote Esophageal Squamous Cell Carcinoma Progression

Advanced Science, EarlyView.
ESCC‐derived exosomal circAP2B1 promotes tumor progression by reprogramming mitochondrial metabolism via the ESRRA/KPNA1/MFN2 axis to induce M2 polarization of macrophages. ABSTRACT Esophageal squamous cell carcinoma (ESCC) remodels the immunosuppressive tumor microenvironment via exosome‐mediated intercellular communication.
Yiru Wang, Gang Feng, Youyu Wang, Ruihao Liang, Haixia Pan, Kai Lei   +5 more
wiley   +1 more source

New Ruthenium (III) complexes with antitumor activity: design, synthesis and characterization

, 2013
Cisplatin was introduced in 1978 in clinical practice for the cancer treatment. In spite of the highly successful use of this drug, it shows several side effects and drug resistance.
Valletta E, PIVETTA, TIZIANA, TUVERI, ROSSANA, ISAIA, FRANCESCO, Melis R, Trudu F, PANI, ALESSANDRA   +6 more
core  

Magneto‐NIR‐II‐Programmed Cascade Nanozymes Unlocking Blood–Brain Barrier Translocation and Autophagic Resistance in Glioblastoma

Advanced Science, EarlyView.
Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu, Yundi Wu, Shuai Zhang, Hongjuan Zhao, Jiping Zheng, Shiyang Shao, Jianqiang Chen, Xilong Wu   +7 more
wiley   +1 more source

Stimuli-responsive platinum and ruthenium complexes for lung cancer therapy. [PDF]

Front Pharmacol, 2022
Zhang C, Kang T, Wang X, Song J, Zhang J, Li G.   +5 more
europepmc   +1 more source

Trustworthy Multimodal Attention Framework for Creep Rupture Life Prediction Under Data‐Scarce Conditions: A Case Study on IN718

Advanced Science, EarlyView.
An attention‐based multimodal deep learning framework is developed to predict the creep life of Ni‐based superalloys by fusing processing parameters with microstructural micrographs. The model achieves high accuracy (R2 = 0.92), aligns with metallurgical principles by capturing δ‐phase influence, and incorporates uncertainty quantification, offering a ...
Haopeng Lv, Dayong Wu, Ziyuan Rao, Qian Wang, Haikun Ma, Jie Kang, Wang Li, Huicong Dong, Yandong Wang, Zhinan Yang, Ru Su   +10 more
wiley   +1 more source

Effect of the µ-Diphosphine Bridging Ligand on the Cytotoxic Activity of Homodinuclear Ruthenium Complexes. [PDF]

Molecules
Roufosse B, Jiménez-Monroy KL, Marschner C, van de Laarschot J, Loftus O, Cleij TJ, Prince S, Blom B.   +7 more
europepmc   +1 more source

A Small‐Molecule DEPTAC Rescues Cognitive Deficits by Targeted Dephosphorylation of Pathological Tau

Advanced Science, EarlyView.
TP2 is a fully synthetic small‐molecule dephosphorylation‐targeting chimera that recruits endogenous PP2A‐Bα to Tau, enabling targeted removal of pathological phosphate modifications. In two tauopathy mouse models, systemic TP2 reduces Tau pathology, preserves neuronal and synaptic integrity, improves neuroimmune homeostasis, and rescues cognition ...
Fei Sun, Yang Liu, Qiuzhi Zhou, Qingyuan Hu, Weixia Wang, Yue Xiao, Jingfen Su, Guanting Liu, Miaomiao Sun, Lixia Chen, Hua Li, Ying Yang, Jian‐Zhi Wang   +12 more
wiley   +1 more source

Heterometallic Multinuclear Ruthenium Complexes as Cytotoxic Agents. [PDF]

Biomedicines
Kostova I.
europepmc   +1 more source

Ruthenium Complexes with Protic Ligands: Influence of the Position of OH Groups and π Expansion on Luminescence and Photocytotoxicity. [PDF]

Int J Mol Sci, 2023
Oladipupo OE, Prescott MC, Blevins ER, Gray JL, Cameron CG, Qu F, Ward NA, Pierce AL, Collinson ER, Hall JF, Park S, Kim Y, McFarland SA, Fedin I, Papish ET.   +14 more
europepmc   +1 more source