Results 151 to 160 of about 30,146 (272)

Pathogenesis of Vitiligo: Integrating Immune and Non‐Immune Cell Crosstalk

The Journal of Dermatology, Volume 53, Issue 2, Page 188-199, February 2026.
ABSTRACT Vitiligo is an acquired autoimmune disease characterized by depigmented macules resulting from melanocyte loss. It is a complex multifactorial disorder in which genetic predisposition is combined with environmental factors; however, its detailed etiology remains unclear.
Shintaro Inoue
wiley   +1 more source

Ruthenium Complexes in Protein Science: Heading a New Generation of Therapeutic and Analytical Tools

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
This review presents the latest advances in the development of ruthenium complexes within the field of protein science, highlighting their potential applications in biomedical and bioanalytical fields. Abstract Ruthenium complexes are distinguished by their versatile coordination chemistry, redox behaviors and photochemical properties. In recent years,
Liyan Zhang, Yun Chen, Sylvestre Bonnet
wiley   +2 more sources

Ruxolitinib Cream in Adolescents/Adults with Atopic Dermatitis Meeting Severity Thresholds for Systemic Therapy: Exploratory Analysis of Pooled Results from Two Phase 3 Studies

Dermatology and Therapy
Introduction Standard therapy for patients with mild to moderate atopic dermatitis (AD) typically includes topical therapies; however, patients with more extensive AD and/or AD refractory to topical therapy may benefit from systemic treatment ...
Eric L. Simpson, Leon Kircik, Andrew Blauvelt, Howard Kallender, Daniel Sturm, Mingyue Wang, Lawrence F. Eichenfield   +6 more
doaj   +1 more source

Off‐Label Use of Topical Ruxolitinib in Dermatology: A Systematic Literature Review and Current Perspectives [PDF]

Marco Spadafora, Serena Morsia, Vito Di Lernia, Shaniko Kaleci, Giovanni Pellacani, Caterina Longo   +5 more
openalex   +1 more source

Targeting Overexpressed IDO in Stromal Cells as a Potential Therapeutic Strategy in Multiple Myeloma

Cancer Science, Volume 117, Issue 2, Page 325-334, February 2026.
IDO expression in stromal cells was upregulated by MM cells via the JAK–STAT1–NF‐κB–IRF1 signaling pathway. JAK inhibitor abolished IDO and IRF1 upregulation. ABSTRACT Stromal cells are an essential component of the tumor microenvironment (TME) in multiple myeloma (MM). Indoleamine 2,3‐dioxygenase 1 (IDO), an enzyme that metabolizes tryptophan (Trp) to
Toru Ebina, Masaki Ri, Yoshiaki Marumo, Tomoyuki Nakamura, Hirokazu Sasaki, Yoshiko Oshima, Takahiro Nakashima, Shinya Hagiwara, Arisa Asano, Shiori Kinoshita, Tomotaka Suzuki, Tomoko Narita, Ayako Masaki, Takaomi Sanda, Kazufumi Yamagata, Kohmei Kubo, Hirokazu Komatsu, Hirotake Sakuraba, Shinsuke Iida   +18 more
wiley   +1 more source

Six‐Year Trends in Real‐World Data Use for Post‐Marketing Surveillance of New Medical Products in Japan

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT The Ministerial Ordinance on Good Post‐Marketing Study Practice for Drugs was amended by the Ministry of Health, Labour and Welfare (MHLW) in 2018 to clearly define post‐marketing database studies (DBS) as a measure of pharmacovigilance activities for approved medical products in Japan.
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

Well‐being in German patients with vitiligo in genital and visible areas – a pilot study

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 2, Page 208-214, February 2026.
Summary Background Only a few studies exist on the psychosocial impact of vitiligo in German patients, in particular those affected in genital and visible body areas. Methods This monocentric pilot study aimed to assess well‐being of adult patients with vitiligo and to compare sex, age, and clinical characteristics between patients with and without ...
Janne Ohlenbusch, Rachel Sommer, Kerstin Steinbrink, Markus Böhm   +3 more
wiley   +1 more source

Wohlbefinden bei Patienten mit Vitiligo mit Beteiligung der sichtbaren Hautareale und der Genitalregion in Deutschland– eine fragebogengestützte Pilotstudie

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 2, Page 208-215, February 2026.
Zusammenfassung Hintergrund Bislang existieren nur wenige Studien zu den psychosozialen Auswirkungen von Vitiligo bei deutschen Patienten. Patienten und Methodik Ziel dieser monozentrischen Pilotstudie war es, das Wohlbefinden und die Lebensqualität erwachsener Patienten mit Vitiligo zu erfassen und diese Parameter hinsichtlich Geschlecht, Alter und ...
Janne Ohlenbusch, Rachel Sommer, Kerstin Steinbrink, Markus Böhm   +3 more
wiley   +1 more source

Pulmonary arterial hypertension exacerbated by ruxolitinib [PDF]

, 2015
Harrison, C, Howard, L, Low, AT, Tulloh, RMR   +3 more
core   +2 more sources

Tofacitinib‐Induced Weight Gain in Context: comment on the article by Wollenhaupt et al.

ACR Open Rheumatology, Volume 8, Issue 2, February 2026.
Andriko Palmowski, Frank Buttgereit, David Simon, Arnd Kleyer, Norman Michael Drzeniek   +4 more
wiley   +1 more source