Results 1 to 10 of about 53,373 (308)

Reactions with Hydrazonoyl Halides. 31. Synthesis of Some New Pyrrolidino[3,4-c]pyrazolines, Pyrazoles, and Pyrazolo[3,4-d]pyridazines

Molecules, 2000
Pyrrolidino[3,4-c]pyrazoline and pyrazole derivatives were synthesized via reactions of a substituted hydrazonoyl bromide with N-arylmaleimides and active methylene reagents, respectively. Synthesized pyrazoles were reacted with hydrazine hydrate to give
Nagla A. Ahmed, Mohamed M. M. Sallam, Hussien F. Zohdi, Abdou O. Abdelhamid   +3 more
doaj   +1 more source

Synthesis and Antimicrobial Evaluation of Some Heterocyclic Chalcone Derivatives

Molecules, 2011
Some new heterocyclic compounds containing isoxazole, pyrazole and oxadiazole ring systems were prepared from various chalcones. The synthesized compounds have been characterized by elemental analysis and spectral methods.
Essam Mohamed Sharshira, Nagwa Mohamed Mahrous Hamada   +1 more
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Two isostructural 3-(5-aryloxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-1-(thiophen-2-yl)prop-2-en-1-ones: disorder and supramolecular assembly

Acta Crystallographica Section E: Crystallographic Communications, 2020
Two new chalcones containing both pyrazole and thiophene substituents have been prepared and structurally characterized. 3-(3-Methyl-5-phenoxy-1-phenyl-1H-pyrazol-4-yl)-1-(thiophen-2-yl)prop-2-en-1-one, C23H18N2O2S (I), and 3-[3-methyl-5-(2-methylphenoxy)
Mohammed A. E. Shaibah, Hemmige S. Yathirajan, Nagaraj Manju, Balakrishna Kalluraya, Ravindranath S. Rathore, Christopher Glidewell   +5 more
doaj   +1 more source

Synthesis, Crystal Structure, and Supramolecular Understanding of 1,3,5-Tris(1-phenyl-1H-pyrazol-5-yl)benzenes

Molecules, 2017
Understanding the supramolecular environment of crystal structures is necessary to facilitate designing molecules with desirable properties. A series of 12 novel 1,3,5-tris(1-phenyl-1H-pyrazol-5-yl)benzenes was used to assess the existence of planar ...
Marcos A. P. Martins, Alexandre R. Meyer, Paulo R. S. Salbego, Daniel M. dos Santos, Guilherme A. de Moraes, Helio G. Bonacorso, Nilo Zanatta, Clarissa P. Frizzo, Manfredo Hörner   +8 more
doaj   +1 more source

Ultrasound-promoted iodination of pyrazoles in aqueous medium

Orbital: The Electronic Journal of Chemistry, 2012
Several pharmacological activities have been devoted to pyrazole containing molecules. In particular, 4-iodopyrazoles have been employed as key starting materials in cross-coupling chemistry and metal-iodine exchange reactions that focus on the synthesis
Jéssica Kunsminskas, Lucas Pizutti, Cristiano Raminelli   +2 more
doaj   +1 more source

Synthesis, Spectroscopic Characterization, Structural Analysis, and Evaluation of Anti-Tumor, Antimicrobial, and Antibiofilm Activities of Halogenoaminopyrazoles Derivatives

Antibiotics
New haloaminopyrazole derivatives differing in the number of pyrazole nuclei 4a–f and 5a–e, respectively, were synthesized and characterized by 1H-NMR, 13C-NMR, IR, UV-Vis, and elemental analysis.
Christina Zalaru, Florea Dumitrascu, Constantin Draghici, Marilena Ferbinteanu, Isabela Tarcomnicu, Maria Marinescu, Zenovia Moldovan, George Mihai Nitulescu, Rodica Tatia, Marcela Popa   +9 more
doaj   +1 more source

Multicomponent Synthesis of New Fluorescent Boron Complexes Derived from 3-Hydroxy-1-phenyl-1H-pyrazole-4-carbaldehyde

Molecules
Novel fluorescent pyrazole-containing boron (III) complexes were synthesized employing a one-pot three-component reaction of 3-hydroxy-1-phenyl-1H-pyrazole-4-carbaldehyde, 2-aminobenzenecarboxylic acids, and boronic acids.
Viktorija Savickienė, Aurimas Bieliauskas, Sergey Belyakov, Eglė Arbačiauskienė, Algirdas Šačkus   +4 more
doaj   +1 more source

Synthesis of New 3-Heteroarylindoles as Potential Anticancer Agents

Molecules, 2016
2-(3-(1H-Indol-3-yl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)-4-substituted-5-(substituted diazenyl)thiazoles and 2-(1H-indol-3-yl)-9-substituted-4,7-disubstituted pyrido[3,2-e][1,2,4]triazolo[4,3-a]pyrimidin-5(7H)-ones were synthesized via reaction of ...
Abdou O. Abdelhamid, Sobhi M. Gomha, Nadia A. Abdelriheem, Saher M. Kandeel   +3 more
doaj   +1 more source

New Pyrazolyl Thioureas Active against the Staphylococcus Genus

Pharmaceuticals
To meet the urgent need for new antibacterial molecules, a small library of pyrazolyl thioureas (PTUs) was designed, synthesized and tested against difficult-to-treat human pathogens.
Anna Maria Schito, Debora Caviglia, Susanna Penco, Andrea Spallarossa, Elena Cichero, Bruno Tasso, Chiara Brullo   +6 more
doaj   +1 more source

Assessment of Anticancer Properties of Synthesized Pyrazole-Acridine Derivative on SH-SY5Y Human Neuroblastoma Cells

Düzce Tıp Fakültesi Dergisi
Aim: This study aimed to synthesize a novel pyrazole acridine derivative (3-ACH) and evaluate its anticancer properties on SH-SY5Y human neuroblastoma cells.Material and Methods: The pyrazole-4-carbaldehyde derivative was cyclized with dimedone and p ...
Muna Elmusa, Mohammadreza Dastourı, Rahmi Kasımoğulları, Hümeyra Yılmaz, Fatıma Elmusa, Yusuf Küçükbağrıaçık   +5 more
doaj   +1 more source