Results 31 to 40 of about 53,373 (308)

SUBSTITUTED 4-NITROSOPYRAZOLES IN THE DIELS-ALDER REACTION

open access: yesSiberian Journal of Life Sciences and Agriculture, 2021
Background. 4-Nitrosopyrazoles have become widespread in the pharmaceutical industry and in chemistry due to their high reactivity and biological activity. However, the interaction of 3,5-substituted 4-nitroso-1H-pyrazoles with diene hydrocarbons has not
Darya S. Volkova   +4 more
doaj   +1 more source

Synthesis and Characterization of 3-Methyl-1-(4-(trifluoromethyl)phenyl)indeno [1,2-c]pyrazol-4(1H)-one

open access: yesMolbank, 2022
Pyrazoles have potential applications in the agrochemical and medicinal chemistry industries as pesticides, anti-inflammatory medications, and antitumor drugs. Fluorinated fused-ring pyrazoles may also possess medicinally useful properties.
Linh Lam, Sang H. Park, Joseph Sloop
doaj   +1 more source

Nickel-Catalyzed, One-Pot Synthesis of Pyrazoles

open access: yesChemistry Proceedings, 2022
Recently, multi-component, one-pot reactions have been shown to be efficient and environmentally friendly methods compared to traditional, linear-step syntheses.
Nassima Medjahed   +4 more
doaj   +1 more source

Preparation of novel acyl pyrazoles and triazoles by means of oxidative functionalization reactions

open access: yesHeterocyclic Communications, 2023
Novel acyl pyrazoles and acyl triazoles have been prepared by means of the oxidative amidation of aldehydes in the presence of the requisite azole. Yields range from modest to good in both cases, and some limitations of the substrate scope have been ...
Wadey Geoffrey P.   +3 more
doaj   +1 more source

Noval 1-substituted-3,5-dimethyl-4-[(substituted phenyl) diazenyl] pyrazole derivatives: Synthesis and pharmacological activity

open access: yesJournal of Saudi Chemical Society, 2015
Several-1-carbothioamide-3,5-dimethyl-4-[(substituted phenyl) diazenyl] pyrazoles 2a–d, 1-(pyridine-4-ylcarbonyl)-3,5-dimethyl-4-[(substituted phenyl) diazenyl] pyrazoles 3a–d, 1-(5-chloro-6-fluoro-1,3-benzothiazole-2-yl)thiocarbamoyl-3,5-dimethyl-4 ...
Sabir Hussain, Deepika Kaushik
doaj   +1 more source

Engineered Enzymes Enable Selective N‐Alkylation of Pyrazoles With Simple Haloalkanes

open access: yesAngewandte Chemie, 2020
Selective alkylation of pyrazoles could solve a challenge in chemistry and streamline synthesis of important molecules. Here we report catalyst‐controlled pyrazole alkylation by a cyclic two‐enzyme cascade.
Ludwig L. Bengel   +5 more
semanticscholar   +1 more source

Recent Advances in Synthesis and Properties of Nitrated-Pyrazoles Based Energetic Compounds

open access: yesMolecules, 2020
Nitrated-pyrazole-based energetic compounds have attracted wide publicity in the field of energetic materials (EMs) due to their high heat of formation, high density, tailored thermal stability, and detonation performance.
Shi-Jie Zhang   +6 more
semanticscholar   +1 more source

PYRAZOLE [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1892
n ...
openaire   +1 more source

Design and synthesis of pyrazole derivatives for in vitro screening to protect angiotensin-converting enzyme 2 human cells against COVID-19

open access: yesCurrent Medicine Research and Practice, 2021
Background: ACE2 is a receptor for Corona virus. COVID-19 (coronavirus) is a deadly virus which can enter the human body through 'angiotensin-converting enzyme 2' human cells, hardly damages the respiratory system. On severe infection on these cells make
Ganesh N Yallappa   +2 more
doaj   +1 more source

SOCl2 catalyzed cyclization of chalcones: Synthesis and spectral studies of some bio-potent 1H pyrazoles

open access: yesBulletin of the Chemical Society of Ethiopia, 2014
Some aryl-aryl 1H pyrazoles have been synthesised by cyclization of aryl chalcones and hydrazine hydrate in the presence of SOCl2. The yields of the pyrazoles are more than 85%.
K. Ranganathan   +5 more
doaj   +1 more source

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