Results 11 to 20 of about 18,189 (198)
Synthesis of tetrasubstituted pyrazoles containing pyridinyl substituents [PDF]
Beilstein Journal of Organic Chemistry, 2017 A synthesis of tetrasubstituted pyrazoles containing two, three or four pyridinyl substituents is described. Hence, the reaction of 1,3-dipyridinyl-1,3-propanediones with 2-hydrazinopyridine or phenylhydrazine, respectively, affords the corresponding 1,3,
Josef Jansa +6 more
doaj +9 more sources
Synthesis of Dihydrooxepino[3,2-c]Pyrazoles via Claisen Rearrangement and Ring-Closing Metathesis from 4-Allyloxy-1H-pyrazoles [PDF]
Molecules, 2018 Synthesis of novel pyrazole-fused heterocycles, i.e., dihydro-1H- or 2H-oxepino[3,2-c]pyrazoles (6 or 7) from 4-allyloxy-1H-pyrazoles (1) via combination of Claisen rearrangement and ring-closing metathesis (RCM) has been achieved.
Yoshihide Usami +3 more
doaj +2 more sources
Synthesis of Dihydropyrano[3,2-c]pyrazoles via Double Bond Migration and Ring-Closing Metathesis [PDF]
Molecules, 2019 Three types of pyrazole-fused heterobicycles, i.e., 1,5-, 1,7-, and 2,5-dihydropyrano[3,2-c]pyrazoles, were synthesized from 4-allyloxy-1H-pyrazoles. A sequence of the Claisen rearrangement of 4-allyloxy-1H-pyrazoles, ruthenium-hydride-catalyzed double ...
Yoshihide Usami +5 more
doaj +2 more sources
New Series of Pyrazoles and Imidazo-Pyrazoles Targeting Different Cancer and Inflammation Pathways [PDF]
Molecules, 2021 (1) Background: different previously synthesized pyrazoles and imidazo-pyrazoles showed interesting anti-angiogenic action, being able to interfere with ERK1/2, AKT and p38MAPK phosphorylation in different manners and with different potency; (2) Methods:
Maria Grazia Signorello +5 more
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Regioselective Synthesis of C3-Hydroxyarylated Pyrazoles [PDF]
, 2021 Pyrazoles are ubiquitous structures in medicinal chemistry. We report the first regioselective route to C3-hydroxyarylated pyrazoles obtained through reaction of pyrazole N-oxides with arynes using mild conditions.
Darren J. Derksen +15 more
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Rhodium(III)-Catalyzed Oxidative Coupling of 5-Aryl-1H-pyrazoles with Alkynes and Acrylates [PDF]
, 2011 Rhodium(III)-Catalyzed Oxidative Coupling of 5-Aryl-1H-pyrazoles with Alkynes and Acrylates[RhCp*Cl(2)](2)-catalyzed oxidative coupling of 5-aryl-1H-pyrazoles with alkynes and acrylates has been achieved using Cu(OAc)(2) as an oxidant.
李兴伟, Zhao, Miao, Li, Xingwei
core +1 more source
Journal of Saudi Chemical Society, 2015 Several-1-carbothioamide-3,5-dimethyl-4-[(substituted phenyl) diazenyl] pyrazoles 2a–d, 1-(pyridine-4-ylcarbonyl)-3,5-dimethyl-4-[(substituted phenyl) diazenyl] pyrazoles 3a–d, 1-(5-chloro-6-fluoro-1,3-benzothiazole-2-yl)thiocarbamoyl-3,5-dimethyl-4 ...
Sabir Hussain, Deepika Kaushik
doaj +1 more source
Current Medicine Research and Practice, 2021 Background: ACE2 is a receptor for Corona virus. COVID-19 (coronavirus) is a deadly virus which can enter the human body through 'angiotensin-converting enzyme 2' human cells, hardly damages the respiratory system. On severe infection on these cells make
Ganesh N Yallappa +2 more
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Direct C–H Alkenylation of Functionalized Pyrazoles [PDF]
, 2016 We have developed inter- and intramolecular C–H alkenylation reactions of pyrazoles. The catalyst, derived from Pd(OAc)2 and pyridine, enabled the oxidative alkenylation of pyrazoles containing a variety of functional groups at the C4 position ...
Su Jin Han (1433359) +2 more
core +1 more source