Results 21 to 30 of about 37,807 (249)
Antibacterial pyrazoles: tackling resistant bacteria.
Future Medicinal Chemistry, 2022 Bacterial resistance to antibiotics threatens our progress in healthcare, modern medicine, food production and ultimately life expectancy. Antibiotic resistance is a global concern, which spreads rapidly across borders and continents due to rapid travel ...
Mohammad A Alam
semanticscholar +1 more source
ACS Omega, 2021 An efficient taurine-catalyzed green multicomponent approach has been described for the first time to synthesize densely substituted therapeutic core dihydropyrano[2,3-c]pyrazoles.
Ghanshyam Mali +6 more
semanticscholar +1 more source
SUBSTITUTED 4-NITROSOPYRAZOLES IN THE DIELS-ALDER REACTION
Siberian Journal of Life Sciences and Agriculture, 2021 Background. 4-Nitrosopyrazoles have become widespread in the pharmaceutical industry and in chemistry due to their high reactivity and biological activity. However, the interaction of 3,5-substituted 4-nitroso-1H-pyrazoles with diene hydrocarbons has not
Darya S. Volkova +4 more
doaj +1 more source
Molbank, 2022 Pyrazoles have potential applications in the agrochemical and medicinal chemistry industries as pesticides, anti-inflammatory medications, and antitumor drugs. Fluorinated fused-ring pyrazoles may also possess medicinally useful properties.
Linh Lam, Sang H. Park, Joseph Sloop
doaj +1 more source
Preparation of novel acyl pyrazoles and triazoles by means of oxidative functionalization reactions
Heterocyclic Communications, 2023 Novel acyl pyrazoles and acyl triazoles have been prepared by means of the oxidative amidation of aldehydes in the presence of the requisite azole. Yields range from modest to good in both cases, and some limitations of the substrate scope have been ...
Wadey Geoffrey P. +3 more
doaj +1 more source
Carbamidine-substituted Pyrazoles [PDF]
Nature, 1951 THE ease with which 1-substituted pyrazoles may be converted into the free imino compounds varies with the nature of the 1-substituent and the reacting substance. Thus, 1,3,5-trimethyl pyrazole may be nitrated1 and 1-phenyl pyrazole reduced to the pyrazoline2 without loss of the N-methyl or N-phenyl groups respectively.
F L, SCOTT, C M B, MURPHY, J, REILLY
openaire +2 more sources
Engineered Enzymes Enable Selective N‐Alkylation of Pyrazoles With Simple Haloalkanes
Angewandte Chemie, 2020 Selective alkylation of pyrazoles could solve a challenge in chemistry and streamline synthesis of important molecules. Here we report catalyst‐controlled pyrazole alkylation by a cyclic two‐enzyme cascade.
Ludwig L. Bengel +5 more
semanticscholar +1 more source
Journal of Saudi Chemical Society, 2015 Several-1-carbothioamide-3,5-dimethyl-4-[(substituted phenyl) diazenyl] pyrazoles 2a–d, 1-(pyridine-4-ylcarbonyl)-3,5-dimethyl-4-[(substituted phenyl) diazenyl] pyrazoles 3a–d, 1-(5-chloro-6-fluoro-1,3-benzothiazole-2-yl)thiocarbamoyl-3,5-dimethyl-4 ...
Sabir Hussain, Deepika Kaushik
doaj +1 more source
Recent Advances in Synthesis and Properties of Nitrated-Pyrazoles Based Energetic Compounds
Molecules, 2020 Nitrated-pyrazole-based energetic compounds have attracted wide publicity in the field of energetic materials (EMs) due to their high heat of formation, high density, tailored thermal stability, and detonation performance.
Shi-jie Zhang +6 more
semanticscholar +1 more source