Results 241 to 250 of about 30,146 (272)

STK405759 targets microtubules, modulates STAT1, and enhances ruxolitinib efficacy in myeloproliferative neoplasms. [PDF]

open access: yesAm J Cancer Res
Rozic G   +7 more
europepmc   +1 more source

JAK1/2 Inhibition Delays Cachexia and Improves Survival through Increased Food Intake

open access: yes
Dantas E   +25 more
europepmc   +1 more source

Ruxolitinib

Reactions Weekly, 2018
Ruxolitinib, formerly known as INCB018424 or INC424, is a potent and selective oral inhibitor of Janus kinase (JAK) 1 and JAK2. Ruxolitinib has been approved for the treatment of myelofibrosis (MF) by the US Food and Drug Administration (FDA) in 2011 and by the European Medicines Agency (EMA) in 2012, followed by the approval for the treatment of ...
Ajayi, Stefanie   +6 more
  +7 more sources

Ruxolitinib

Reactions Weekly, 2014
Ruxolitinib, formerly known as INCB018424 or INC424, is a potent and selective oral inhibitor of JAK1 and JAK2. Ruxolitinib has been approved for the treatment of myelofibrosis, which is characterized, biologically, by the activation of the JAK-STAT pathway and, clinically, by bone marrow fibrosis, splenomegaly, abnormal blood counts, and poor quality ...
Becker, Heiko   +3 more
openaire   +4 more sources

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