Results 81 to 90 of about 2,517 (166)

Potent neutralizing human monoclonal antibodies protect from Rift Valley fever encephalitis

JCI Insight
Rift Valley fever (RVF) is an emerging arboviral disease affecting both humans and livestock. In humans, RVF displays a spectrum of clinical manifestations, including encephalitis. To date, there are no FDA-approved vaccines or therapeutics for human use,
Kaleigh A. Connors, Nathaniel S. Chapman, Cynthia M. McMillen, Ryan M. Hoehl, Jackson J. McGaughey, Zachary D. Frey, Morgan Midgett, Connor Williams, Douglas S. Reed, James E. Crowe Jr., Amy L. Hartman   +10 more
doaj   +1 more source

Maternal vaccination with live-attenuated Rift Valley fever virus protects offspring via immune transfer

npj Vaccines
Rift Valley fever virus (RVFV) causes high rates of spontaneous abortions and neonatal mortality in ruminants resulting in severe socioeconomic and public health consequences.
Austin T. Hertel, Cynthia M. McMillen, Ryan M. Hoehl, Dominique J. Barbeau, Anita K. McElroy, Amy L. Hartman   +5 more
doaj   +1 more source

Rift Valley fever virus targets the maternal-foetal interface in ovine and human placentas.

PLoS Neglected Tropical Diseases, 2020
BACKGROUND:Rift Valley fever virus (RVFV) is an arbovirus of the order Bunyavirales that causes severe disease in ruminants and humans. Outbreaks in sheep herds are characterised by newborn fatalities and abortion storms.
Judith Oymans, Paul J Wichgers Schreur, Lucien van Keulen, Jet Kant, Jeroen Kortekaas   +4 more
doaj   +1 more source

Field studies of Culex mosquitoes in Tanzania and Kenya: A systematic review motivated by changing Rift Valley fever virus transmission patterns

Medical and Veterinary Entomology, Volume 39, Issue 4, Page 689-700, December 2025.
There were 275 studies reporting Culex abundance, 17 of which explicitly stated the motivation for the study was RVFV. Despite most studies being motivated by other topics, there was good coverage of studies reporting mosquito sampling in areas associated with the risk of RVFV outbreaks. Studies were c.
Catherine Andrews, Joshua Longbottom, Joel Lutomiah, Jennifer S. Lord   +3 more
wiley   +1 more source

Examination of RVFV CBD cap-binding.

, 2019
A) Thermal stability of RVFV CBD and influenza A virus PB2 cap-binding domain was tested in presence and absence of different concentrations (1, 2, 5, 7.5, 10 mM) of m7GTP, m7GpppG, GTP and ATP.
Nadja Gogrefe (4026011), Stephan Günther (218223), Sophia Reindl (2829590), Maria Rosenthal (2830790)   +3 more
core   +1 more source

Landscapes associated with Japanese encephalitis virus in Australia reflect the functional biogeography of waterbirds

Ecosphere, Volume 16, Issue 10, October 2025.
Abstract Japanese encephalitis virus (JEV), a zoonotic, mosquito‐borne virus, has broad circulation across the Central Indo‐Pacific biogeographical region (CIPBR) and has recently expanded dramatically within this region across southeastern Australia over the summer of 2021–2022.
Michael G. Walsh, Cameron Webb, Victoria Brookes   +2 more
wiley   +1 more source

Stem-based peptides inhibit both RVFV and VSV.

, 2013
Peptides were screened for inhibition of the pseudotyped reporter viruses RVF-VSV-luc (A and C) and VSV-luc (B and D). Virus was incubated with peptide RVFV-6, -7, -8, -9, or -10 (A, B) or serial dilutions of RVFV-6, RVFV-10, or the scrambled peptides ...
Shannon L. Taylor (434470), Anders Wallqvist (43485), Jeffrey W. Koehler (259360), Catherine V. Badger (457971), Monica M. Ogg (457973), Daniel R. Ripoll (29910), Kristin W. Spik (457970), Rebecca J. Grant (457972), Connie S. Schmaljohn (239773), Jeffrey M. Smith (239771), Mary C. Guttieri (457974), Robert F. Garry (115213)   +11 more
core   +1 more source

RVFV IgG seropositivity by age group and location.

, 2022
RVFV IgG seropositivity by age group and location.
Bryson Alberto Ndenga (4694332), Karren Nyumbile Shaita (13046773), Eleonora Migliore (12596146), Francis Maluki Mutuku (4694317), Keli Nicole Gerken (13046761), Said Malumbo (13046770), A. Desiree LaBeaud (8319543), Izabela Mauricio Rezende (13046776), Eduardo Palacios Fabre (13046767), Gladys Adhiambo Agola (13046764)   +9 more
core   +1 more source

Serological evidence of rift valley fever Phlebovirus and Crimean-Congo hemorrhagic fever orthonairovirus infections among pygmies in the east region of Cameroon

Virology Journal, 2018
Background Rift Valley Fever Phlebovirus (RVFV) and Crimean-Congo Hemorrhagic Fever Orthonairovirus (CCHFV) specific antibodies had been documented among humans in urban settings of the southwestern and northern Cameroon in the late 1980s.
Serge Alain Sadeuh-Mba, Gide Martial Yonga Wansi, Maurice Demanou, Antoine Gessain, Richard Njouom   +4 more
doaj   +1 more source

Recent Advances in Humoral Immunity Dysregulation in Severe Fever With Thrombocytopenia Syndrome Virus (SFTSV) Infection: A Systematic Review

Health Science Reports, Volume 8, Issue 10, October 2025.
ABSTRACT Background and Aims Severe fever with thrombocytopenia syndrome virus (SFTSV) infection causes profound dysregulation of humoral immunity, leading to immunopathology and impaired viral clearance. However, the mechanisms underlying B cell dysfunction and inadequate antibody responses remain poorly defined.
Hongyan Hou, Xu Yuan, Rujia Chen, Zhigang Xiong, Shiji Wu, Feng Wang   +5 more
wiley   +1 more source