Results 101 to 110 of about 51,241 (200)
Journal of Lipid Research, 2010 Cholesterol 7α-hydroxylase (CYP7A1) plays a key role in maintaining lipid and bile salt homeostasis as it is the rate-limiting enzyme converting cholesterol to bile acids. Deficiency of CYP7A1 leads to hyperlipidemia in man and mouse.
Shi-Ying Cai +4 more
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Do bold shakeups of the learning-teaching agreement work? A commognitive perspective on a LUMOS low lecture innovation [PDF]
, 2014 Mathematics undergraduates, and their lecturers, often describe the transition into university mathematics as a process of enculturation into new mathematical practices and new ways of constructing and conveying mathematical meaning (Nardi, 1996 ...
Nardi, Elena
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Veterinary Medicine International, 2012 Canine osteosarcoma (OS) is an aggressive malignant bone tumor. Prognosis is primarily determined by clinical parameters. Vitamin D has been postulated as a novel therapeutic option for many malignancies.
John Davies +5 more
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eLifeType II nuclear receptors (T2NRs) require heterodimerization with a common partner, the retinoid X receptor (RXR), to bind cognate DNA recognition sites in chromatin. Based on previous biochemical and overexpression studies, binding of T2NRs to chromatin
Liza Dahal +5 more
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Vitamin D Represses Retinoic Acid-Dependent Transactivation of the Retinoic Acid Receptor-ß2 Promoter: The AF-2 Domain of the Vitamin D Receptor Is Required for Transrepression [PDF]
, 1999 10 pages, 8 figures.Retinoic acid (RA)-dependent activation of the RA receptor ß2 (RARß2) gene in embryonal carcinoma cells is mediated by binding of retinoid receptor heterodimers (RAR/RXR) to a RA response element (RARE) located closely to the TATA box.
Aranda, Ana, Jiménez Lara, Ana M.
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Genes and Environment, 2019 Background Surface waters receive a variety of organic pollutants via wastewater discharge, and sediment represents a sink for hydrophobic contaminants. In this study, we used in vitro yeast-based reporter gene assays and a Bacillus subtilis Rec-assay to
Pei-Hsin Chou +5 more
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Power-free values of the polynomial t_1...t_r - 1
, 2011 Let k, r > 1 be two integers. We prove an asymptotic formula for the number of k-free values of the r variables polynomial t_1...t_r - 1 over the integral points of [1, x]^r.Comment: Final ...
Boudec, Pierre Le
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Improvement of Skin Condition Through RXR Alpha-Activating Materials
BiomoleculesRetinol is well-known anti-aging material in the cosmetics industry, owing to its proven superior efficacy both in vitro and in vivo. Despite its high efficacy, retinol is associated with limitations, such as skin irritation and its potential ...
Sanghyun Ye +4 more
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Private capital formation: Short- and long-run crowding-in (out) effects in ASEAN, 1971-99 [PDF]
This study presents an empirical assessment of the factors that have stimulated (deterred) private investment in the Association of Southeast Asian Nations (ASEAN) economies during the past three decades. The results for the short-run suggest that output
Anthony Bende-Nabende, Jim Slater
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Scientific ReportsDespite advances in therapy, multiple myeloma (MM) largely remains incurable, emphasizing the need for new strategies to overcome drug resistance. Ferroptosis is an iron-dependent cell death pathway that may present a therapeutic vulnerability in MM, but
Jian Wu +7 more
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