Results 91 to 100 of about 136,524 (172)

Evaluation d'un vecteur associé à l'adénovirus recombinant de sérotype 4 (AAV4) pour le traitement par thérapie génique d'un modèle canin de l'amaurose congénitale de Leber (le chien Briard RPE65-/-)

, 2007
Les vecteurs dérivés des adéno-associated virus (AAV) permettent un transfert de gène ef cace et stable dans la rétine. Les futures applications possibles de ce traitement par transfert de gène en ophtalmologie seront le traitement de dégénérescences ...
ROLLING, Fabienne, LE MEUR, Guylène
core  

Polydatin Alleviates APAP‐Induced Hepatotoxicity by Targeting C/EBPβ to Suppress the NLRP3 Inflammasome Signaling Pathway

iNew Medicine, EarlyView.
PD alleviates APAP‐induced ALI by inhibiting the NLRP3 inflammasome signaling pathway. C/EBPβ is identified as a direct target via multimethod validation. PD promotes the deacetylation of C/EBPβ via Sirt1. The Sirt1/C/EBPβ/NLRP3 signaling axis is defined for PD's hepatoprotective effect.
Tian‐Yu Yang, Chen Wang, Yi Ding, Wei‐Kang Zhang, Ling Zheng, Li Yue, Lei Zhang   +6 more
wiley   +1 more source

Molecular epidemiology of foot-and-mouth disease viruses collected from Khartoum, Blue Nile, and Northern States of Sudan (2019-2022). [PDF]

Sci Rep
Ragab M, Almofti YA, Rauouf YA, Knowles NJ, King DP, Wadsworth J, Hicks HM, Saeed H, Algalil OA, Albokhadaim I, Alameen AO, Kandeel M, Alhojaily S, Al-Hammadi MA, Hussen J, Shukry M, Al-Trad B.   +16 more
europepmc   +1 more source

Development and External Validation of Logistic Regression Models Integrating Conventional Complete Blood Count and Cell Population Data for Predicting RT‐PCR–Confirmed Dengue

Journal of Clinical Laboratory Analysis, EarlyView.
We developed logistic regression models integrating routine complete blood count (CBC) parameters and analyzer‐derived cell population data (CPD) to predict RT‐PCR–confirmed dengue infection and evaluated their performance across internal and external settings.
Lin‐Chen Hsu, Yu‐Ching Weng, Wen‐Chun Liu   +2 more
wiley   +1 more source

Prevalence, Serotype Distribution, and Antimicrobial Resistance of <i>Streptococcus agalactiae</i> Among Pregnant Women in Greece: A Retrospective Study. [PDF]

J Clin Med
Chasiakou A, Kaparos G, Chasiakou S, Demeridou S, Koumaki V, Tsakris A.   +5 more
europepmc   +1 more source

Preliminary Development and Assessment of a Multiplex Assay for Human Papillomavirus Antibody Detection Using Commercial L1 Proteins

Journal of Clinical Laboratory Analysis, EarlyView.
This study developed and assessed a new multiplex assay for the simultaneous detection of antibodies against multiple Human Papillomavirus (HPV) types. Using recombinant L1 protein, the assay quantifies IgG and IgA responses in human plasma, enabling comprehensive immune profiling across multiple high‐risk cancer‐associated HPV genotypes. This approach
Arash Aslanabadi, Maryam Karimi, Laura Powell, Lisa Schumaker, Ashley Shutt, Mahsa Hojabri, Rahim Abbasi, Søren M. Bentzen, Kevin J. Cullen, Trevor A. Crowell, Rebecca G. Nowak, Mohammad M. Sajadi   +11 more
wiley   +1 more source

Spatiotemporal co-circulation of four dengue serotypes across Mexico, 2020-2025: A space-time scan analysis. [PDF]

PLoS One
Mendoza-Cano O, Trujillo X, Ríos-Silva M, Bricio-Barrios JA, Lugo-Radillo A, Tapia-Vargas R, Venegas-Ramírez J, Ríos-Bracamontes EF, Cuevas-Arellano HB, Cárdenas Y, Aquino-Santos R, Jiménez-Vieyra IA, Uribe-Ramos JM, Benites-Godínez V, Martínez-Díaz TE, López-Rojas M, García-Solórzano A, Murillo-Zamora E.   +17 more
europepmc   +1 more source

Trends in hospitalizations for vaccine‐preventable diseases in the United States from 2014 to 2024

Journal of Hospital Medicine, EarlyView.
Abstract Background and Objectives Vaccination rates have declined in recent years, resulting in outbreaks of vaccine‐preventable diseases (VPDs) among children. We aimed to evaluate VPD hospitalization rates from 2014 to 2024 and to report associated trends in outcomes including intensive care utilization, mortality, readmissions, and costs.
Nathan M. Money, Erin Sullivan, Hannah Rector, Corrie E. McDaniel, Jessica L. Markham, Mersine A. Bryan   +5 more
wiley   +1 more source

Systematic analysis of global O-serotype prevalence of neonatal extraintestinal pathogenic Escherichia coli: A protocol integrating previous research and bioinformatics databases. [PDF]

PLoS One
Zhang D, Zou P, Xiao R, Li J, Sheng S, Xiao R, Liang X, Wang Y.   +7 more
europepmc   +1 more source

Absence of progressive liver disease after treatment in children with chronic hepatitis C: A nationwide registry study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives In adults with chronic hepatitis C (CHC) and advanced fibrosis, hepatocellular carcinoma (HCC) surveillance is recommended after achieving a sustained virologic response (SVR). However, post‐SVR surveillance strategies for children remain unclear. The aim of this study was to assess the durability of SVR and determine an appropriate
Hitoshi Tajiri, Mitsuyoshi Suzuki, Yuri Etani, Yoshinori Ito, Koichi Ito, Tomoya Fukuoka, Tatsuki Mizuochi   +6 more
wiley   +1 more source