Results 161 to 170 of about 136,566 (245)

Gene therapy for epilepsy: An emerging, promising approach for a serious neurological disorder

open access: yesJournal of Internal Medicine, Volume 299, Issue 3, Page 302-327, March 2026.
Abstract Gene therapy is emerging as a groundbreaking strategy for treating epilepsy, offering new hope to patients who do not respond to conventional medications. Despite advancements in anti‐seizure treatments, nearly 30%–40% of individuals with epilepsy continue to experience uncontrolled seizures, highlighting the urgent need for more effective and
Marco Ledri, Merab Kokaia
wiley   +1 more source

Culicoides species involved in the BTV‐3 epidemic, the Netherlands, 2023–2024

open access: yesMedical and Veterinary Entomology, Volume 40, Issue 1, Page 111-122, March 2026.
A high amount of Culicoides‐midges were captured using Onderstepoort light traps on farms with animals infected with bluetongue serotype 3 (BTV‐3) at the beginning of the outbreak in 2023. Species, sex and parity of the captured Culicoides‐midges were morphologically determined and gravid and parous Culicoides‐midges have been selected and pooled for ...
Mathilde Uiterwijk   +9 more
wiley   +1 more source

Cardiomyocyte‐Derived USP20 Attenuates Diabetic Cardiomyopathy by Facilitating the Degradation of STING and Mitigating STING‐Mediated Inflammation

open access: yesThe FASEB Journal, Volume 40, Issue 3, 15 February 2026.
USP20 directly binds to STING and promotes the degradation of STING through the autophagy pathway by deubiquitinating p62 via its active site C154, thereby alleviating myocardial inflammation and improving ventricular remodeling and heart failure induced by diabetes. ABSTRACT Although extensive clinical and basic research has been conducted on diabetic
Yixin Zhou   +15 more
wiley   +1 more source

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