The Journal of Physiology, EarlyView.Abstract figure legend The genetic inactivation of one Mcu allele leads to sex‐specific changes in neuronal function in adult mice, that is, the firing of action potentials and the relationship between cytosolic and mitochondrial Ca2+ levels. The ability to produce NAD(P)H by stimulated neural tissue is largely preserved in male mice but delayed in ...
Jenna Gray +16 more
wiley +1 more source
Genomic characterization of mobile genetic elements associated with antimicrobial resistance in <i>Streptococcus pneumoniae</i> from Australia. [PDF]
Microb GenomSunmonu GT +5 more
europepmc +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Beat‐locked mitochondrial ATP transients reveal modular, sex‐specific bioenergetic control during excitation–contraction coupling. A, each action potential activates L‐type CaV1.2 channels, producing a Ca2+ influx that triggers ryanodine receptors (RyR2) and elicits SR Ca2+ release.
Paula Rhana +2 more
wiley +1 more source
Establishment and optimization of an <i>E. coli</i> urinary tract infection model in Göttingen minipigs with strain recovery and characterization. [PDF]
Front ImmunolLübbers J +10 more
europepmc +1 more source
Circular RNAs: Unlocking new avenues in cardiometabolic disease management
The Journal of Physiology, EarlyView.Abstract figure legend In the heart circular RNAs (circRNAs) function as microRNA sponges, interact with proteins and can even undergo translation. Advances in bioinformatics now enable their identification through high‐throughput RNA sequencing, whereas computational analyses reveal differential expression in cardiac disease settings.
Kimberley M. Mellor +4 more
wiley +1 more source
Long-term antibody dynamics challenge the paradigm of lifelong homotypic immunity to dengue virus. [PDF]
Proc Natl Acad Sci U S AAndrade J +17 more
europepmc +1 more source
Glia, Volume 74, Issue 8, August 2026.Neuronal contact‐induced expression of S1PR1 in astrocytes is regulated by JAK‐STAT3 signaling. Astrocytic S1PR1 modulates cortical astrocyte morphogenesis. Astrocytic S1PR1 regulates astrocyte territorial overlap/tiling in a competition dependent manner.
Jean Patrick M. Gonzales +9 more
wiley +1 more source
Yin Yang 1 Specifically Supports the Development of Olig2 Positive Cerebellar Astrocytes
Glia, Volume 74, Issue 8, August 2026.Cerebellar Olig2 positive astrocytes are most abundant in the cerebellar nuclei. Cerebellar astrocytes expressing Olig2 have unique gene expression profiles. Yin Yang 1 specifically supports the development of astrocytes expressing Olig2. Deletion of YY1 during development increases numbers of astrocytes expressing Olig2 but hinders their ...
Masoumeh Zarei‐Kheirabadi +9 more
wiley +1 more source
Prophage-mediated lysogenic conversion drives virulence evolution and genomic plasticity in <i>Streptococcus suis</i> serotype 9. [PDF]
Microbiol SpectrWen Z +8 more
europepmc +1 more source
A Novel Green Method for Producing Medical‐Grade Chitosan From Loligo plei Squid Pens
Journal of Applied Polymer Science, Volume 143, Issue 25, July 5, 2026.This work demonstrates a sustainable and simplified process for the production of medical‐grade chitosan from the feathers of the squid Loligo plei, employing mild chemical treatments to preserve the integrity of the polymer while achieving high purity and performance.
Talita Martins +7 more
wiley +1 more source