Results 211 to 220 of about 147,345 (227)

AQP1 Corrects Acinar Cells’ Secretion Deficits in Sjögren's Disease

Oral Diseases, EarlyView.
ABSTRACT Introduction Sjögren's disease (SjD) is a systemic autoimmune disease characterized by dry mouth, dry eyes, and profound fatigue. Preclinical studies suggest that AQP1 gene expression in salivary glands corrects salivary hypofunction in preclinical and clinical studies of radiation‐induced xerostomia and improves salivary and lacrimal function
Paola Perez, Blake M. Warner, Youngmi Ji, Sandra Afione, Thomas J. F. Pranzatelli, Margaret E. Beach, Zohreh Khavandgar, Margie Grisius, Eileen Pelayo, Daniel Martin, NIDCD/NIDCR Genomics and Computational Biology Core, Alan N. Baer, John A. Chiorini   +12 more
wiley   +1 more source

The spatial structure of dengue transmission in Kamphaeng Phet Thailand. [PDF]

PLoS Negl Trop Dis
Ooi SH, Huang AT, Kaewhiran S, Farmer A, Buddhari D, Li T, Gandhi J, Pollio AR, Hang J, Conte MA, Cummings DAT, Anderson K, Salje H.   +12 more
europepmc   +1 more source

Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders

Oral Diseases, EarlyView.
ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz, Shankara N. Varadarajan, Viktor Drel, Prakash Arullampalam, Mahmoud I. Shoulkamy, Ahmed Al‐Sabi, Brij B. Singh   +6 more
wiley   +1 more source

Molecular epidemiology of foot-and-mouth disease viruses collected from Khartoum, Blue Nile, and Northern States of Sudan (2019-2022). [PDF]

Sci Rep
Ragab M, Almofti YA, Rauouf YA, Knowles NJ, King DP, Wadsworth J, Hicks HM, Saeed H, Algalil OA, Albokhadaim I, Alameen AO, Kandeel M, Alhojaily S, Al-Hammadi MA, Hussen J, Shukry M, Al-Trad B.   +16 more
europepmc   +1 more source

XAB06, a glyco-humanized broad-spectrum anti-<i>Pseudomonas aeruginosa</i> polyclonal antibody, protects mice in a lethal sepsis model. [PDF]

Antimicrob Agents Chemother
Royer P-J, Graur G, Varin M, Vanhove B, Duvaux O, Bassissi F.   +5 more
europepmc   +1 more source

Antibiotic‐mediated immune modulation in periodontitis

Periodontology 2000, EarlyView.
Abstract Periodontitis is a chronic inflammatory disease affecting the supporting structures of the teeth. Although initiated by dysbiotic microbial communities, its progression is largely driven by the host's uncontrolled inflammatory response. While antibiotics have conventionally been employed in periodontitis therapy for their antimicrobial ...
Lina J. Suárez, R. M. Arce, Camila Pinheiro Furquim, Cristiane Gonçalves, Alpdogan Kantarci, Magda Feres, Nidia C. Castro dos Santos   +6 more
wiley   +1 more source

DENV-2 Genetic Diversity and Variation in Antibody-Dependent Enhancement in Lao PDR. [PDF]

Int J Mol Sci
Xayavong D, Somoulay V, Khamphaphongphane B, Xangxayarath P, Osako H, Yamasato K, Ihara M, Balingit JC, Ngwe Tun MM, Morita K, Hidano A, Hasebe F, Takamatsu Y.   +12 more
europepmc   +1 more source

Of mice and men—The emerging oral–gut–brain axis of health and disease

Periodontology 2000, EarlyView.
Abstract Objectives Oral health's inextricable links to systemic health are highlighted by the emerging oral–gut–brain axis and other well‐known axes. There is growing evidence of a complex oral–gut–brain axis linking mouth and gut microbiomes with the central nervous system.
Yvonne L. Hernandez‐Kapila, Daniel J. Weisenberger   +1 more
wiley   +1 more source

Performance evaluation of clinical diagnostic kits for Group B <i>Streptococcus</i> available in China. [PDF]

Microbiol Spectr
Su R, Chen X, Lu S, Zhou Y, Liu Y, Huang Q, Zhang Y, Zheng X, Li M, Hou W, Yang K, Ye H, Lv Y, Tang Z, Ge S.   +14 more
europepmc   +1 more source

From mouth to brain: Linking periodontal and peri‐implant dysbiosis to systemic inflammation and neuropathology

Periodontology 2000, EarlyView.
Abstract Background/Aim Growing evidence suggests that imbalances occurring within the human microbiota and deregulation of the host immune response may play a significant role in the development of neurodegenerative diseases. Materials and Methods A comprehensive narrative review of the latest experimental, clinical, and epidemiological insights was ...
Emilio A. Cafferata, Frank Schwarz, Jaime Díaz‐Zúñiga, Alpdogan Kantarci   +3 more
wiley   +1 more source