Results 51 to 60 of about 141,120 (242)

Broad cross-T cell immunity between emerging SARS-CoV-2 serotypes waved by spike-signature mutations

Emerging Microbes and Infections
Since its emergence in late 2019, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has continuously threatened human health through constantly arising variants with iterative immune escape abilities.
Yuanyuan Guo, Jinmin Tian, Peipei Guo, Xin Wang, Bingli Shang, Junying She, Mengjie Yang, George F. Gao, Jun Liu   +8 more
doaj   +1 more source

The Widespread Multidrug-Resistant Serotype O12 Pseudomonas aeruginosa Clone Emerged through Concomitant Horizontal Transfer of Serotype Antigen and Antibiotic Resistance Gene Clusters

mBio, 2015
The O-specific antigen (OSA) in Pseudomonas aeruginosa lipopolysaccharide is highly varied by sugar identity, side chains, and bond between O-repeats. These differences classified P. aeruginosa into 20 distinct serotypes. In the past few decades, O12 has
Sandra Wingaard Thrane, Véronique L. Taylor, Luca Freschi, Irena Kukavica-Ibrulj, Brian Boyle, Jérôme Laroche, Jean-Paul Pirnay, Roger C. Lévesque, Joseph S. Lam, Lars Jelsbak   +9 more
doaj   +1 more source

Emergence and re-emergence of two major diseases in France (bluetongue) and in Mauritius (foot-and-mouth) [PDF]

, 2017
L’émergence en France continentale de la fièvre catarrhale ovine (FCO) causée en 2006 par le virus de sérotype 8 (BTV-8) puis en 2007, par le virus de sérotype 1 (BTV-1) a constitué une surprise totale. Fin 2012, six ans après l’introduction de la FCO,
Bakkali-Kassimi, Labib, Vitour, Damien, Romey, Aurore, Belbis, Guillaume, Bakkali Kassimi, Labib, Gorna, Kamila, Relmy, Anthony, Bréard, Emmanuel, Zientara, Stéphan, Blaise-Boisseau, Sandra, Sailleau, Corinne, Cardinale, Éric, Viarouge, Cyril   +12 more
core   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Première observation d'une épidémie de septicémie hémorragique due à Pasteurella multocida sérotype B6 au Nord-Cameroun

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1994
Pour la première fois au Cameroun, une souche de Pasteurella multocida de sérotype B6 a été isolée d'un foyer de septicémie hémorragique sur des zébus dans la région de Maga (Province de l'Extrême-Nord du pays).
Arnaud Martrenchar, B.M. Njanpop
doaj   +1 more source

Actualités sur deux maladies virales vectorielles zoonotiques en Europe : West Nile et Usutu - Réémergence du sérotype 8 du virus de la fièvre catarrhale ovine (FCO)

, 2023
National audienceTwo zoonotic or potentially zoonotic flaviviruses have emerged in Europe, the West Nile and Usutu viruses. The Usutu virus, whose cycle is similar to that of West Nile, circulates in Europe and in France (since 2015).
Gonzalez, Gaëlle, Zientara, Stéphan
core   +1 more source

Noninvasive Focal Gene Delivery into the Cerebellum of Non‐Human Primates using Focused Ultrasound

Advanced Science, EarlyView.
Focal and non‐invasive viral vector delivery in non‐human primates remains a major challenge in translational neuroscience. Low‐intensity focused ultrasound was used to transiently open the blood–brain barrier and enable targeted gene delivery to the cerebellum.
Noelia Esteban‐García, José A. Pineda‐Pardo, Inés Trigo‐Damas, Marta Gutiérrez, Marta Castillo‐Ortiz, Megan Carrillo, Alejandro Reinares‐Sebastian, Víctor Medina‐Chavarrías, Itay Rachmilevitch, Masahiko Takada, José A. Obeso, Javier Blesa   +11 more
wiley   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source

Virulence and draft genome sequence overview of multiple strains of the swine pathogen Haemophilus parasuis. [PDF]

PLoS ONE, 2014
Haemophilus parasuis is the cause of Glässer's disease in swine, which is characterized by systemic infection resulting in polyserositis, meningitis, and arthritis.
Susan L Brockmeier, Karen B Register, Joanna S Kuehn, Tracy L Nicholson, Crystal L Loving, Darrell O Bayles, Sarah M Shore, Gregory J Phillips   +7 more
doaj   +1 more source

Herba Lysimachiae Polysaccharide‐Modified Selenium Nanoparticles Alleviate Oxidative Injury in Kidney Stones via TOMM22‐Regulated Mitophagy Activation

Advanced Science, EarlyView.
HLP‐SeNPs, a Lysimachia christinae polysaccharide‐modified selenium nanoparticle, treat kidney stones by downregulating TOMM22 expression, which reduces PINK1 translocation into mitochondria and promotes its retention on the outer mitochondrial membrane.
Junyi Yang, Guoruiyu Lyu, Wenlong Wan, Dongfeng Yuan, Jiabo Li, Yongqi Wang, Baokang Wang, Zhilong Ma, Yuanyuan Yang, Yang Xun, Xiao Yu   +10 more
wiley   +1 more source